[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552002":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":56,"collaborators":26,"id":58,"slug":26,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":26,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":26,"overallStatus":76,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Shanghai Mental Health Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Theta Stimulation(6Hz, generated with electrodes of 2kHz and 2.005kHz)","EXPERIMENTAL","Session1#T1(10min)+DTI(15min) Session2#rsfMRI(8min)+rsfMRI-Theta tTIs(8min)+rsfMRI(8min)+TASK fMRI-Theta TI(20min)",[13],"Device: tTIS on dACC, theta frequency (5 Hz)",{"label":15,"type":16,"description":17,"interventionNames":18},"High Frequency Stimulation(generated with two electrodes of 2kHz)","SHAM_COMPARATOR","Session1#T1(10min)+DTI(15min) Session2#rsfMRI(8min)+rsfMRI-HF tTIs(8min)+rsfMRI(8min)+TASK fMRI-HF TI(20min)",[19],"Device: tTIS on dACC, High frequency",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","tTIS on dACC, theta frequency (5 Hz)","Device: Transcranial electric stimulation device\n\nThe first pair of electrodes continuously outputs a current with a frequency of f1 = 2 kHz, while the second pair continuously outputs a current with a frequency of f2 = 2.006 kHz. According to the principle of time-domain coherence, an alternating electric field with a frequency of f2-f1 = 6 Hz can be generated in the target area. The experimental group receives a stimulation intensity of 2mA for 20 minutes. The optimal electrode position and current parameters are determined by using the MIDA head electric field model.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"tTIS on dACC, High frequency","The first pair of electrodes continuously outputs a current with a frequency of f1 = 2 kHz, while the second pair continuously outputs a current with a frequency of f2 = 2 kHz. The sham group receives a stimulation intensity of 2mA for 20 minutes. The optimal electrode position and current parameters are determined by using the MIDA head electric field model.",[15],[32],{"name":33,"affiliation":5,"role":34},"Min Zhao, M.D, Ph.D","STUDY_CHAIR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Tianzhen Chen, M.D, Ph.D","CONTACT","021-34773523","vomchan@hotmail.com",[42],{"facility":5,"status":26,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Shanghai","Shanghai Municipality","200000","China",{"type":48,"coordinates":49},"Point",[50,51],121.45806,31.22222,{"lat":51,"lon":50},[54],{"name":33,"role":38,"phone":55,"phoneExt":26,"email":26},"18017311005",{"type":57,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100552002",false,"NCT06467422","Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder","Exploring the Role and Neural Mechanisms of Transcranial Temporal Interference Stimulation Modulating the Dorsal Anterior Cingulate Cortex on Risky Decision-making and Impulse Control in Gambling Disorder","Inclusion Criteria:\n\n* Aged 18-60, male or female, right handed;\n* With 9 or more years of education, and able to cooperate in completing the questionnaire assessment and behavioural tests.\n* Meets the DSM-5 diagnostic criteria for gambling addiction;\n* Previous gambling behaviour of not less than 1 year's duration (at least one gambling session per week or more);\n* Normal or corrected normal vision and hearing;\n* Agrees to cooperate in completing the follow-up assessment;\n* No history of neurological problems or head injury; and no skin sensitivity.\n* Agree to cooperate in completing the follow-up assessment;\n* No metal implantation in the head, no history of neurological problems or head injury, and no skin sensitivity.\n\nExclusion Criteria:\n\n* Suffering from severe cognitive dysfunction, such as a history of head trauma, cerebrovascular disease, epilepsy, etc., use of cognitive-promoting medications in the last 6 months;\n* Other psychoactive substance abuse or dependence in the last 5 years (except nicotine).","MALE","18 Years","60 Years",{"count":68,"type":69},30,"ESTIMATED","INTERVENTIONAL",[72],"NA","The purpose of this research is to investigate the effect of transcranial temporal interference stimulation (tTIS) targeting the dorsal anterior cingulate cortex in patients with gambling disorder.",[75],"Gambling Disorder","NOT_YET_RECRUITING","2024-06-20",{"date":79,"type":80},"2024-06-21","ACTUAL",{"date":77,"type":69},{"date":83,"type":69},"2025-06-01",{"name":5,"class":6},1]