[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100419707":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":11,"studyPopulation":11,"armGroups":24,"interventions":35,"overallOfficials":11,"centralContacts":11,"locations":40,"responsibleParty":60,"collaborators":11,"id":64,"slug":11,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":11,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":11,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":11,"overallStatus":43,"whyStopped":11,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"The First Affiliated Hospital of Soochow University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":11},[9],{"measure":10,"description":11,"timeFrame":12},"Acute Graft-Versus-Host Disease",null,"90 days after haploidentical hematopoietic stem cell transplantation",[14,16],{"measure":15,"description":11,"timeFrame":12},"overall survival",{"measure":17,"description":11,"timeFrame":12},"Event free survival",{"allocation":19,"interventionModel":20,"interventionModelDescription":11,"primaryPurpose":21,"observationalModel":11,"timePerspective":11,"maskingInfo":22},"NON_RANDOMIZED","SINGLE_GROUP","PREVENTION",{"masking":23,"maskingDescription":11,"whoMasked":11},"NONE",[25,31],{"label":26,"type":27,"description":28,"interventionNames":29},"with auto-FMT","EXPERIMENTAL","The patients in the experimental group took autologous fecal bacteria capsule about 3 weeks after bone marrow transplantation.",[30],"Other: autologous fecal bacteria",{"label":32,"type":33,"description":34,"interventionNames":11},"empty capsule","NO_INTERVENTION","The patients in this group took empty capsule about 3 weeks after bone marrow transplantation",[36],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":11},"autologous fecal bacteria","autologous fecal bacteria transplantation",[26],[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Ye Zhao","RECRUITING","Suzhou","Jiangsu","215006","China","CN",{"type":50,"coordinates":51},"Point",[52,53],120.59538,31.30408,{"lat":53,"lon":52},[56],{"name":42,"role":57,"phone":58,"phoneExt":11,"email":59},"CONTACT","+8651267780410","mutation@163.com",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Qi Xiao-Fei","Principal Investigator","100419707",false,"NCT04745221","Efficacy and Safety of Auto-FMT in Preventing aGVHD","Efficacy and Safety of Autologous Fecal Bacteria Transplantation in Preventing Acute Graft Versus Host Disease After Haploidentical Hematopoietic Stem Cell Transplantation: a Multicenter, Open, Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* Haplo-HSCT patients; Bacteroidetes \\>0.1%; inverse Simpson diversity ≥2\n\nExclusion Criteria:\n\n* Gastrointestinal diseases；Age\\>60; or Age\\\u003C10；Probiotics or prebiotics were taken before enrollment","ALL","18 Years","60 Years",{"count":74,"type":75},100,"ESTIMATED","INTERVENTIONAL",[78],"NA","To evaluation the efficacy and safety of autologous fecal bacteria transplantation in preventing acute graft versus host disease after haploidentical hematopoietic stem cell transplantation. Bone marrow transplant patients were recruited.",[81],"Graft Versus Host Disease, Acute","2026-05-28",{"date":84,"type":85},"2026-06-01","ACTUAL",{"date":87,"type":85},"2021-03-01",{"date":89,"type":75},"2027-03-01",{"name":5,"class":6},1]