[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618264":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":11,"locations":26,"responsibleParty":46,"collaborators":11,"id":48,"slug":11,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":11,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":11,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":11,"overallStatus":29,"whyStopped":11,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"MiKS Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Frozen Platelet-Rich Plasma","EXPERIMENTAL",null,[13],"Other: Platelet Rich Plasma",{"label":15,"type":16,"description":11,"interventionNames":17},"Platelet-Rich Plasma","ACTIVE_COMPARATOR",[13],[19,23],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"Platelet Rich Plasma","Platelet-rich plasma stored by freezing",[9],{"type":6,"name":20,"description":24,"armGroupLabels":25,"otherNames":11},"Fresh Platelet-Rich Plasma",[15],[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Arthroscopic Surgery Unit, MiKS Hosptial","RECRUITING","Vitoria-Gasteiz","Araba\u002FÁlava","01010","Spain",{"type":35,"coordinates":36},"Point",[37,38],-2.67268,42.84998,{"lat":38,"lon":37},[41],{"name":42,"role":43,"phone":44,"phoneExt":11,"email":45},"Diego Delgado","CONTACT","0034 945 25 20 77","diego.delgado@hospitalmiks.com",{"type":47,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100618264",false,"NCT07329361","Efficacy and Safety of Intra-articular Injections of Frozen Platelet-Rich Plasma in Patients With Knee Osteoarthritis","Efficacy and Safety of Intra-articular Injections of Frozen Platelet-Rich Plasma in Patients With Knee Osteoarthritis: Randomized Control Trial","Inclusion Criteria:\n\n* Patients of both sexes.\n* Aged between 40 and 85 years old.\n* Diagnosed with osteoarthritis through clinical radiological examination.\n* Joint pain equal to or less than 75 points on the KOOS (pain).\n* Radiological severity grades 1, 2, and 3 according to the Ahlbäck scale.\n* Indication for intra-articular PRP infiltration.\n* Body Mass Index values between 20 and 35.\n* Negative serological tests for syphilis, HIV, HBV, and HCV.\n* Possibility of observation during the follow-up period.\n* Signature of informed consent.\n\nExclusion Criteria:\n\n* Body mass index \\>35\n* Diagnosed polyarticular disease.\n* Previous arthroscopy in the last year.\n* Severe mechanical deformity.\n* Intra-articular hyaluronic acid injection in the last 12 months.\n* Intra-articular corticosteroid or PRP injection in the last 6 months.\n* Systemic autoimmune rheumatic disease (connective tissue diseases and systemic necrotizing vasculitis).\n* Anemia or other hematological disorders.\n* Positive serological tests for SYPHILIS, HIV, HBV, and HCV.\n* Undergoing immunosuppressive treatments.\n* Poorly controlled diabetes mellitus.\n* Patients allergic to paracetamol.\n* Pregnancy or breastfeeding.","ALL","40 Years","85 Years",{"count":58,"type":59},60,"ESTIMATED","INTERVENTIONAL",[62],"NA","Evaluation of intra-articular injections in knee osteoarthritis using frozen-stored PRP. Compared with intra-articular injections of PRP applied at the time of collection.",[65],"Knee Osteoarthristis","2025-12-26",{"date":68,"type":69},"2026-01-09","ACTUAL",{"date":71,"type":59},"2025-12-16",{"date":73,"type":59},"2027-12-31",{"name":5,"class":6},1]