[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100514341":3},{"organization":4,"outcomesModule":7,"designInfo":42,"detailedDescription":45,"studyPopulation":46,"armGroups":47,"interventions":73,"overallOfficials":99,"centralContacts":104,"locations":109,"responsibleParty":126,"collaborators":41,"id":130,"slug":41,"hasResults":131,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":41,"eligibilityCriteria":135,"healthyVolunteers":131,"sex":136,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":41,"studyType":142,"phases":41,"briefSummary":143,"conditions":144,"keywords":41,"overallStatus":112,"whyStopped":41,"lastUpdateSubmitDate":146,"lastUpdatePostDateStruct":147,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":155},{"fullName":5,"class":6},"Mackay Medical College","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":41,"otherOutcomes":41},[9,13,16,20,23,26,29,32,35,38],{"measure":10,"description":11,"timeFrame":12},"Urodynamic study (intravesical pressure)","intravesical pressure (cmH2O)","form the baseline to the post-treatment measurement (about 6 month post)",{"measure":14,"description":15,"timeFrame":12},"Urodynamic study (abdominal pressure)","abdominal pressure (cmH2O)",{"measure":17,"description":18,"timeFrame":19},"Urodynamic study (detrusor pressure)","detrusor pressure (cmH2O)","from the baseline to the post-treatment measurement (about 6 month post)",{"measure":21,"description":22,"timeFrame":19},"Urodynamic study (Infused volume)","infused volume (ml)",{"measure":24,"description":25,"timeFrame":19},"Urodynamic study (voided volume)","voided volume (ml)",{"measure":27,"description":28,"timeFrame":19},"Pad test","The weight of Pad (g) before and after testing",{"measure":30,"description":31,"timeFrame":19},"Bladder diary (voiding frequency)","the daily voiding frequency (times)",{"measure":33,"description":34,"timeFrame":19},"Bladder diary (voiding volume)","the daily voiding volume (ml)",{"measure":36,"description":37,"timeFrame":19},"Questionaire (UDI-6)","The urogenital distress inventory-6 (UDI-6)",{"measure":39,"description":40,"timeFrame":19},"Questionaire (IIQ-7)","incontinence impact questionnaire-7 (IIQ-7)",null,{"allocation":41,"interventionModel":41,"interventionModelDescription":41,"primaryPurpose":41,"observationalModel":43,"timePerspective":44,"maskingInfo":41},"COHORT","RETROSPECTIVE","Urinary incontinence is a common problem among women. The main types include stress incontinence, urge incontinence, and overflow incontinence. Other underlying pathology, such as cancer or neurologic disease can also cause urinary incontinence. To limit the medical expenses and possible complications of surgical treatment, the current treatment guidelines recommend conservative treatment as the first choice. According to American Urological Association (AUA)\u002FSociety of Urodynamics, Female Pelvic Medicine \\& Urogenital Reconstruction (SUFU) guidelines, the first-line treatment for non-neurologic overactive bladder should be behavioral therapy, such as bladder training, water restriction, and pelvic floor muscle training, physiological feedback, pessary, etc. Bladder training aims to increase the time interval between voids, and to increase the bladder capacity by self-adjusted schedules. Pelvic floor muscle training strengthens the pelvic floor muscles to provide urethral support to prevent urine leakage and suppress urgency. There is strong evidence that pelvic floor muscle training is beneficial for stress urinary incontinence.\n\nThe second-line treatment is medication, including anticholinergic drugs and ß3 adrenoceptor-acting agents. Anticholinergic drugs can reduce bladder detrusor contraction, and ß3 adrenoceptor-acting agents can relax the detrusor and increase bladder capacity.","Diagnosed at Mackay Memorial Hospital, the adult female patient was clinically assessed and diagnosed with urinary incontinence. Non-surgical treatments were administered, followed by subsequent monitoring and follow-up.",[48,53,57,61,65,69],{"label":49,"type":41,"description":50,"interventionNames":51},"Bladder training (BT)","Data obtained before and after the training.",[52],"Procedure: BT",{"label":54,"type":41,"description":50,"interventionNames":55},"biofeedback-assisted pelvic floor muscle training (bPFMT)",[56],"Procedure: bPFMT",{"label":58,"type":41,"description":50,"interventionNames":59},"intra-vaginal electric stimulation (iVES)",[60],"Procedure: iVES",{"label":62,"type":41,"description":50,"interventionNames":63},"BT+bPFMT",[64],"Procedure: BT + bPFMT",{"label":66,"type":41,"description":50,"interventionNames":67},"BT+iVES",[68],"Procedure: BT + iVES",{"label":70,"type":41,"description":50,"interventionNames":71},"bPFMT+iVES",[72],"Procedure: bPFMT + iVES",[74,79,83,87,91,95],{"type":75,"name":76,"description":77,"armGroupLabels":78,"otherNames":41},"PROCEDURE","BT","A program of BT (including exercise and muscle training)",[49],{"type":75,"name":80,"description":81,"armGroupLabels":82,"otherNames":41},"bPFMT","A bPFMT program at home",[54],{"type":75,"name":84,"description":85,"armGroupLabels":86,"otherNames":41},"iVES","An iVES program at home",[58],{"type":75,"name":88,"description":89,"armGroupLabels":90,"otherNames":41},"BT + bPFMT","Combination of BT and bPFMT",[62],{"type":75,"name":92,"description":93,"armGroupLabels":94,"otherNames":41},"BT + iVES","Combination of BT and iVES",[66],{"type":75,"name":96,"description":97,"armGroupLabels":98,"otherNames":41},"bPFMT + iVES","Combination of bPFMT and iVES",[70],[100],{"name":101,"affiliation":102,"role":103},"Hui-Hsuan Lau, M.D.","Department of Ear, Nose, and Throat, MacKay Memorial Hospital, Taipei, Taiwan","STUDY_CHAIR",[105],{"name":101,"role":106,"phone":107,"phoneExt":41,"email":108},"CONTACT","+886-975-835928","huihsuan1220@gmail.com",[110],{"facility":111,"status":112,"city":113,"state":41,"zip":41,"country":114,"countryCode":115,"cosmosGeoPoint":116,"geoPoint":121,"contacts":122},"Department of Obstetrics and Gynecology","RECRUITING","New Taipei City","Taiwan","TW",{"type":117,"coordinates":118},"Point",[119,120],121.45703,25.06199,{"lat":120,"lon":119},[123],{"name":124,"role":106,"phone":125,"phoneExt":41,"email":108},"Hui-Hsuan Lau, PhD","+886 975-835928",{"type":127,"investigatorFullName":128,"investigatorTitle":129,"investigatorAffiliation":5,"oldNameTitle":41,"oldOrganization":41},"PRINCIPAL_INVESTIGATOR","Chin-Tsung Shen","The Office of Research and Development staff","100514341",false,"NCT05977231","Efficacy of Conservative Treatments for Urinary Incontinence in Women","Evaluation of Efficacy of Conservative Treatments in Women With Urinary Incontinence","Inclusion Criteria:\n\n* Adult female patient diagnosed with urinary incontinence through clinical assessment\n* Diagnosed at Mackay Memorial Hospital and underwent non-surgical treatment and subsequent follow-up.\n\nExclusion Criteria:\n\n* Choosing invasive or surgical treatment options (such as bladder botulinum toxin injection, urethral sling surgery).\n* Unable to comply with regular follow-up for at least one year.\n* Pregnant women\n* Patients with a history of neuromuscular disorders.","FEMALE","20 Years","100 Years",{"count":140,"type":141},60,"ESTIMATED","OBSERVATIONAL","To conduct a retrospective study to examine the effect of these conservative treatments to the symptoms and quality of life of patients with urinary incontinence. The investigators will use both subjective and objective assessment parameters, such as self-report symptoms, bladder diary, pad test and urodynamic study to access the improvement.",[145],"Urinary Incontinence","2023-07-28",{"date":148,"type":149},"2023-08-04","ACTUAL",{"date":151,"type":149},"2023-01-01",{"date":153,"type":141},"2028-12-31",{"name":5,"class":6},1]