[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574768":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":42,"locations":50,"responsibleParty":71,"collaborators":25,"id":73,"slug":25,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":25,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":25,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":53,"whyStopped":25,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Department of Medical Services Ministry of Public Health of Thailand","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Surgical Glove-Compression Therapy","EXPERIMENTAL","Patients wore double-layered surgical gloves, one size smaller than measured, covered by large cotton gloves on both hands, for 30 minutes before, during, and after chemotherapy.",[13],"Device: Surgical Glove-Compression Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"non-compressive plastic gloves","PLACEBO_COMPARATOR","Patients wore non-compressive plastic gloves, covered by large cotton gloves on both hands, for 30 minutes before, during, and after chemotherapy.",[19],"Device: non-compressive plastic gloves",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","In the intervention group, patients wore double-layered surgical gloves, one size smaller than measured, covered by large cotton gloves on both hands, for 30 minutes before, during, and after chemotherapy.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"In the control group, patients wore non-compressive plastic gloves, covered by large cotton gloves on both hands, for 30 minutes before, during, and after chemotherapy.",[15],[30,33,36,38,40],{"name":31,"affiliation":5,"role":32},"Sunatee Sa-nguansai, M.D.","STUDY_DIRECTOR",{"name":34,"affiliation":5,"role":35},"Saowani Thantaviraya, M.D.","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":5,"role":35},"Kunlatida Maneenil, M.D.",{"name":39,"affiliation":5,"role":35},"Piyawan Tienchaiananda, M.D.",{"name":41,"affiliation":5,"role":35},"Songwit Payapwattanawong, M.D.",[43,47],{"name":34,"role":44,"phone":45,"phoneExt":25,"email":46},"CONTACT","+66805564241","saowani.mook@gmail.com",{"name":31,"role":44,"phone":48,"phoneExt":25,"email":49},"+66896949358","sunatee@hotmail.com",[51],{"facility":52,"status":53,"city":54,"state":54,"zip":55,"country":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Rajavithi Hospital, Medical Oncology Unit","RECRUITING","Bangkok","10400","Thailand",{"type":58,"coordinates":59},"Point",[60,61],100.50144,13.75398,{"lat":61,"lon":60},[64,66,67,68,69,70],{"name":34,"role":44,"phone":65,"phoneExt":25,"email":46},"+668-05564241",{"name":31,"role":44,"phone":48,"phoneExt":25,"email":49},{"name":37,"role":44,"phone":25,"phoneExt":25,"email":25},{"name":39,"role":44,"phone":25,"phoneExt":25,"email":25},{"name":41,"role":44,"phone":25,"phoneExt":25,"email":25},{"name":34,"role":44,"phone":25,"phoneExt":25,"email":25},{"type":72,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100574768",false,"NCT06763575","Efficacy of Surgical Glove-Compression Therapy As a Prevention of Paclitaxel-Induced Peripheral Neuropathy","Efficacy of Surgical Glove-Compression Therapy As a Prevention of Paclitaxel-Induced Peripheral Neuropathy: Randomized Controlled Trial","Inclusion Criteria:\n\n* Signed Informed Consent Form\n* Age 18 years or older at the time of signing Informed Consent Form\n* Patients with any pathological diagnosis of solid tumor, such as breast cancer or lung cancer\n* Patients scheduled to be receiving intravenous paclitaxel or paclitaxel-based regimen every 3 weeks\n\nExclusion Criteria:\n\n* Patients whose received chemotherapeutic agents that could cause neuropathy, e.g. taxane-based or platinum-based chemotherapy and anti-microtubule\n* History of neuropathy\n* History of carpal tunnel syndrome\n* History of allergic reactions to latex or gloves\n* Patients receiving treatments that may treat neuropathy, e.g. amitriptyline, gabapentin, Acetyl L-Carnitine and Ganglioside-monosialic acid, acupuncture, cryotherapy or exercise therapy\n* History of Raynaud phenomenon\n* History of wounds or large scars on hands\n* Pregnancy or breastfeeding\n* History of poorly controlled diabetes; HbA1c\\>6.5","ALL","18 Years",{"count":82,"type":83},36,"ESTIMATED","INTERVENTIONAL",[86],"NA","The aim of this randomized controlled trial (RCT) is to compare the incidence of paclitaxel-induced grade 2 or higher sensory peripheral neuropathy, evaluated using the CTCAE version 5.0, between patients receiving surgical glove-compression therapy (SGCT) and those in the control group.\n\nThe main question is whether SGCT is effective in preventing paclitaxel-induced sensory peripheral neuropathy.\n\n* Intervention group: receive SGCT.\n* Control group: receive non-compressive plastic gloves.",[89],"Paclitaxel-induced Peripheral Neuropathy",[91,9,92],"Paclitaxel","Peripheral Neuropathy","2025-01-02",{"date":95,"type":96},"2025-01-08","ACTUAL",{"date":98,"type":83},"2025-01-01",{"date":100,"type":83},"2026-06-01",{"name":5,"class":6},1]