[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100507272":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":32,"centralContacts":37,"locations":44,"responsibleParty":60,"collaborators":42,"id":63,"slug":42,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":42,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":42,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":42,"overallStatus":47,"whyStopped":42,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Beni-Suef University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PIFB group","ACTIVE_COMPARATOR","patients will receive bilateral ultrasound-guided pecto-intercostal fascial block using 20 ml of bupivacaine 0.25% for each side.",[13],"Procedure: pecto intercostal fascial block using bupivacaine 0.25%",{"label":15,"type":10,"description":16,"interventionNames":17},"LIDOCAINE group","1.5 mg\u002Fkg lidocaine will be administered after induction of anesthesia, then 2mg\u002Fkg\u002Fh lidocaine will be administered with continuous intravenous infusion until the end of the surgery.",[18],"Drug: lidocaine infusion",[20,26],{"type":21,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"PROCEDURE","pecto intercostal fascial block using bupivacaine 0.25%",[9],[25],"Sunnypivacaine",{"type":27,"name":28,"description":16,"armGroupLabels":29,"otherNames":30},"DRUG","lidocaine infusion",[15],[31],"Lignocaine",[33],{"name":34,"affiliation":35,"role":36},"Mariana A mansour, Lecturer","benisuef university hospital,Egypt","PRINCIPAL_INVESTIGATOR",[38],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Mariana A soliman, lecturer","CONTACT","01222960009",null,"mrmrsyk4@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":42,"country":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Benisuef University Hospital","RECRUITING","Banī Suwayf","e\\EYGPT","Egypt",{"type":52,"coordinates":53},"Point",[54,55],31.09785,29.07441,{"lat":55,"lon":54},[58],{"name":59,"role":40,"phone":41,"phoneExt":42,"email":43},"Mariana A Soliman, MD",{"type":36,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"Mariana Soliman","Lecturer of anaesthesia, surgical intensive care and pain managment","100507272",false,"NCT05885230","Efficacy of Ultrasound Guided PIFB Versus Lidocaine Infusion on Postoperative Pain After Sternotomy","The Efficacy of Ultrasound-guided Pecto-Intercostal Fascial Plain Block Versus Lidocaine Infusion on Acute and Chronic Post-sternotomy Pain; A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n1. age between 18 and 75 years.\n2. patient scheduled to undergo elective on-pump cardiac surgery with sternotomy.\n3. American Society of Anesthesiologists classification of physical status \\\u003C IV.\n\nExclusion Criteria:\n\n1. emergency surgery.\n2. off-pump surgery.\n3. redo surgery.\n4. ejection fraction less than 35%.\n5. refusal of the patient.\n6. known hypersensitivity to LA.\n7. chronic opioid use or chronic pain patient.\n8. psychiatric problems or communication difficulties.\n9. liver insufficiency (defined as a serum bilirubin ≥ 34 μmol\u002Fl, albumin ≤ 35 g\u002Fdl, INR ≥ 1.7).\n10. renal insufficiency (defined as a glomerular filtration rate \\\u003C 44 ml\u002Fmin).\n11. obstructive sleep apnea syndrom.\n12. coexisting hematologic disorders.\n13. pregnancy or breastfeeding.",true,"ALL","18 Years","75 Years",{"count":74,"type":75},138,"ESTIMATED","INTERVENTIONAL",[78],"NA","Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-sternoyomy pain syndrome (PSPS) ranges from 33% to 91%. Exact pathogenetic mechanisms for developing chronic pain after sternotomy are unknown. Apart from intraoperative nerve damage and subsequent postoperative neuropathic pain, operation techniques, age, sex, pre-existing pain, genetic and psychosocial factors, severe postoperative pain, and analgesic management are suspected to have an impact on the development of PSPS .",[81],"Cardiac Surgery","2026-06-18",{"date":84,"type":85},"2026-06-23","ACTUAL",{"date":87,"type":85},"2023-05-01",{"date":89,"type":75},"2027-05",{"name":5,"class":6},1]