[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618639":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":32,"responsibleParty":49,"collaborators":25,"id":53,"slug":25,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":25,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":25,"maxAge":61,"enrollmentInfo":62,"targetDuration":25,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":25,"overallStatus":71,"whyStopped":25,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Sohag University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"fixed-dose ESWL","ACTIVE_COMPARATOR","* Start therapeutic\u002Fhigh energy (e.g., 80-100% device max) from therapeutic phase.\n* Total shocks: 2000-3000 adjusted by fragmentation progress and tolerance. Log shocks and cumulative energy.",[13],"Procedure: Extracorporeal shock wave lithotripsy",{"label":15,"type":16,"description":17,"interventionNames":18},"escalating-dose ESWL","EXPERIMENTAL","* Stepwise escalation: increase energy every 500-1000 shocks (example: 20% → 40% → 60% → 80-100%) until therapeutic energy reached.\n* Total shocks: 2000-3000 adjusted by fragmentation progress and tolerance. Log shocks per step and cumulative energy.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Extracorporeal shock wave lithotripsy","Fixed Voltage (experimental): Subjects receive shock wave therapy at a constant energy level (e.g., 20-22 kV) for the entire duration of the session. Standard delivery includes approximately 3,000 shocks at a frequency of 60-90 shocks per minute.\n\nVoltage Ramping (control): Subjects receive shock wave therapy starting at a low energy level (e.g., 6-10 kV) for an initial \"priming\" phase of 100-500 shocks. Energy is then escalated in predefined increments (e.g., 1-2 kV every 250-500 shocks) until reaching the target therapeutic voltage.",[15,9],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"mohammed A Abdelhafez","CONTACT","+201143548707","3elwa97@gmail.com",[33],{"facility":34,"status":25,"city":35,"state":25,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Sohag university Hospital","Sohag","82511","Egypt",{"type":39,"coordinates":40},"Point",[41,42],31.69478,26.55695,{"lat":42,"lon":41},[45],{"name":46,"role":29,"phone":47,"phoneExt":25,"email":48},"ahmed abdelhamed, professor","+201068056074","sharkawiahmed@yahoo.com",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","mohammed Abdelhafez","Urology Resident , sohag hospital university","100618639",false,"NCT07334236","Energy Ramping Versus Fixed Dose ESWL","Energy Ramping Versus Fixed Dose ESWL on Stone-Free Rate (Comparative Study)","Inclusion Criteria:\n\n* Adults ≥18 years.\n* Radiopaque renal or proximal\u002Fmid ureteral stone ≤20 mm.\n* eGFR ≥60 mL\u002Fmin\u002F1.73 m².\n* Fit for ESWL.\n* Able to give informed consent and complete follow up.\n\nExclusion Criteria:\n\n* • Pregnancy.\n\n  * Active, untreated UTI.\n  * Uncorrected bleeding disorder or anticoagulation that cannot be stopped.\n  * Prior ipsilateral renal surgery.\n  * Non radio-opaque stone without reliable imaging.\n  * Inability to tolerate ESWL or required anesthesia.",true,"ALL","80 Years",{"count":63,"type":64},100,"ESTIMATED","INTERVENTIONAL",[67],"NA","This clinical trial compares two techniques of extracorporeal shock wave lithotripsy (ESWL) - energy ramping versus fixed dose - in adult patients with renal stones. The study aims to evaluate stone-free rates, retreatment needs, and safety outcomes across multiple clinical sites in Egypt.",[70],"Renal Calculi","NOT_YET_RECRUITING","2026-01-03",{"date":74,"type":75},"2026-01-12","ACTUAL",{"date":72,"type":64},{"date":78,"type":64},"2026-11-01",{"name":51,"class":6},1]