[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100345533":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":36,"centralContacts":44,"locations":53,"responsibleParty":67,"collaborators":29,"id":71,"slug":29,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":29,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":29,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":55,"whyStopped":29,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"M group","ACTIVE_COMPARATOR","Mannitol infusion",[13],"Procedure: Mannitol infusion",{"label":15,"type":10,"description":16,"interventionNames":17},"D group","Dopamine infusion",[18],"Procedure: Dopamine infusion",{"label":20,"type":10,"description":21,"interventionNames":22},"C group","Adequate hydration",[23],"Procedure: Adequate hydration",[25,30,33],{"type":26,"name":11,"description":27,"armGroupLabels":28,"otherNames":29},"PROCEDURE","Infusion of Mannitol 20% at a dose of 0.5 mg\u002Fkg to the renal graft donor after induction of anesthesia over 15 minutes.",[9],null,{"type":26,"name":16,"description":31,"armGroupLabels":32,"otherNames":29},"Infusion of Dopamine at a dose of 4 microg\u002Fkg\u002Fmin to the renal graft donor after induction of anesthesia till ligation of the renal artery.",[15],{"type":26,"name":21,"description":34,"armGroupLabels":35,"otherNames":29},"Infusion of Ringer Acetate at a rate of 15 ml\u002Fkg\u002Fhr to the renal graft donor after induction of anesthesia till ligation of the renal artery.",[20],[37,41],{"name":38,"affiliation":39,"role":40},"Nazmy E Seif, MD","Kasr Al-Ainy Hospital, Cairo University","STUDY_CHAIR",{"name":42,"affiliation":39,"role":43},"Ahmed M Elbadawy, MD","STUDY_DIRECTOR",[45,50],{"name":38,"role":46,"phone":47,"phoneExt":48,"email":49},"CONTACT","01227400808","+2","drnazmyseif@yahoo.com",{"name":42,"role":46,"phone":51,"phoneExt":48,"email":52},"01064249076","elbadawyahmed89@yahoo.com",[54],{"facility":39,"status":55,"city":56,"state":29,"zip":29,"country":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Cairo","Egypt",{"type":59,"coordinates":60},"Point",[61,62],31.24967,30.06263,{"lat":62,"lon":61},[65,66],{"name":38,"role":46,"phone":47,"phoneExt":48,"email":49},{"name":42,"role":46,"phone":51,"phoneExt":48,"email":52},{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"SPONSOR_INVESTIGATOR","Nazmy Edward Seif","Clinical Professor","100345533",false,"NCT03778944","Enhancing Renal Graft Function During Donor Anesthesia","Renal Graft Functional Enhancement During Donor Anesthesia: A Comparative Study of 3 Modalities","Inclusion Criteria:\n\n* end-stage renal disease, for living-donor kidney transplantation\n\nExclusion Criteria:\n\n* severe cardiac or hepatic dysfunction\n* coagulopathy","ALL","18 Years","60 Years",{"count":81,"type":82},60,"ESTIMATED","INTERVENTIONAL",[85],"NA","Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney. The aim of this study is to assess \\& compare the effectiveness of 3 different modalities in this respect: Mannitol, Dopamine and adequate hydration.",[88,89,90],"Renal Failure Chronic","Transplant;Failure,Kidney","Anesthesia",[92,93,94,95,90],"Mannitol","Dopamine","Perfusion","Renal graft donor","2026-01-08",{"date":98,"type":99},"2026-01-12","ACTUAL",{"date":101,"type":99},"2018-12-20",{"date":103,"type":82},"2026-12",{"name":69,"class":6},1]