About this trial
The goal of this pilot study is to determine if non-invasive brain stimulation during sleep can increase deep sleep in adults with depression. It will also determine if increased deep sleep improves cognitive performance and mood ratings. Participants will be asked to wear a non-invasive device that records their brain activity and delivers transcranial electrical stimulation during sleep. Participants will also wear an actigraphy watch that measures activity levels throughout the study. In addition, participants will complete several cognitive assessments and mood and sleep questionnaires throughout the study.
Eligibility criteria
Qualifiers
Ability to complete overnight sleep study including placement of EEG leads
Ability to read and understand English.
Moderate depression
Self-reported cognitive complaints
Disqualifiers
Previous adverse reaction to transcranial electrical stimulation
Presence of implanted devices (e.g. intracranial device, cochlear implant)
Presence of metal in head (e.g. surgical clip)
Sensitivity or allergy to silver
Trial design
Treatments tested in this trial
- Transcranial Electrical Stimulation (TES)
Treatment groups
Locations
1Sponsors and collaborators
Wake Forest University Health Sciences
Lead sponsor