Enhancing Slow Wave Sleep in Depression

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-80
SponsorWake Forest University Health Sciences

About this trial

The goal of this pilot study is to determine if non-invasive brain stimulation during sleep can increase deep sleep in adults with depression. It will also determine if increased deep sleep improves cognitive performance and mood ratings. Participants will be asked to wear a non-invasive device that records their brain activity and delivers transcranial electrical stimulation during sleep. Participants will also wear an actigraphy watch that measures activity levels throughout the study. In addition, participants will complete several cognitive assessments and mood and sleep questionnaires throughout the study.

Eligibility criteria

Qualifiers

Ability to complete overnight sleep study including placement of EEG leads

Ability to read and understand English.

Moderate depression

Self-reported cognitive complaints

Disqualifiers

Previous adverse reaction to transcranial electrical stimulation

Presence of implanted devices (e.g. intracranial device, cochlear implant)

Presence of metal in head (e.g. surgical clip)

Sensitivity or allergy to silver

Trial design

Treatments tested in this trial

  • Transcranial Electrical Stimulation (TES)

Treatment groups

12 Participants
are divided into 1 treatment group

Locations

1
Wake Forest University Health Sciences27104, Winston-SalemNorth Carolina, United States

Sponsors and collaborators

Wake Forest University Health Sciences

Lead sponsor