[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593731":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":55,"collaborators":57,"id":65,"slug":10,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8,12,15,17,19,21,23],{"label":9,"type":10,"description":11,"interventionNames":10},"ANCA Associated Vasculitis",null,"Case",{"label":13,"type":10,"description":14,"interventionNames":10},"Extramembranous Glomerulopathy","Control",{"label":16,"type":10,"description":14,"interventionNames":10},"Nephrotic Syndrome, Minimal Change",{"label":18,"type":10,"description":14,"interventionNames":10},"Interstitial Nephritis",{"label":20,"type":10,"description":14,"interventionNames":10},"IgA Nephropathy",{"label":22,"type":10,"description":14,"interventionNames":10},"Segmental Hyalinosis",{"label":24,"type":10,"description":14,"interventionNames":10},"Diabetic Nephropathy",[26],{"name":27,"affiliation":5,"role":28},"Marine LIVROZET","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Maxime BRUSSIEUX","CONTACT","+33 1 44 84 17 89","maxime.brussieux@aphp.fr",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},"Laura LE MAO","+33 1 56 09 54 97","laura.le-mao@aphp.fr",[40],{"facility":41,"status":42,"city":43,"state":10,"zip":10,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Georges-Pompidou European Hospital, AP-HP","RECRUITING","Paris","France",{"type":46,"coordinates":47},"Point",[48,49],2.3488,48.85341,{"lat":49,"lon":48},[52],{"name":53,"role":32,"phone":10,"phoneExt":10,"email":54},"Marine Livrozet","marine.livrozet@aphp.fr",{"type":56,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[58,61,63],{"name":59,"class":60},"Ministry of Health, France","OTHER_GOV",{"name":62,"class":60},"Institut National de la Santé Et de la Recherche Médicale, France",{"name":64,"class":6},"National Research Agency, France","100593731",false,"NCT07010250","Epithelial Dysmetabolism and Renal Fibrosis in ANCA Vasculitis","PROTECT-Fi","Inclusion Criteria:\n\n* Patients with an indication for initial diagnostic PBR on native kidney\n* 18 ans ≥ Age ≤ 90 ans\n* Affiliation to french health insurance\n* Patient having given consent\n\nFor the ANCA vasculitis group:\n\n• Diagnosis of ANCA vasculitis retained on renal biopsy with ANCA anti-proteinase 3 (PR3) or ANCA anti-myeloperoxidase (MPO)\n\nFor the control groups:\n\n• Diagnosis retained after the renal biopsy\n\n* Interstitial Nephritis\n* Or glomerular nephropathy such as minimal change nephropathy\n* Or Segmental hyalinosis in itscollapsing form\n* Or Extramembranous Glomerulopathy,\n* Or glomerulopathy with mesangial IgA deposits\n* Or diabetic nephropathy.\n\nExclusion Criteria:\n\n* Kidney transplant patient\n* Patient on dialysis (hemodialysis or peritoneal dialysis)\n* Patient under legal protection, guardianship or curatorship\n* Pregnancy or breastfeeding\n* Enrollement in an interventional study except studies relating to ANCA vasculitis and nephropathy with mesangial IgA deposits.","ALL","18 Years","90 Years",{"count":75,"type":76},146,"ESTIMATED","OBSERVATIONAL","The project is to explore in humans the hypothesis of the link between the alteration of tubulo-interstitial metabolism and the rate of deterioration of renal function by comparing various nephropathies.",[9,13,16,18,20,22,80],"Diabetic Nephropathies",[82,83],"nephropathy","cohort","2026-06-29",{"date":86,"type":87},"2026-06-30","ACTUAL",{"date":89,"type":87},"2025-11-03",{"date":91,"type":76},"2029-11-02",{"name":5,"class":6},1]