[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623903":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":34,"collaborators":38,"id":43,"slug":7,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":7,"studyType":55,"phases":7,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"University Children's Hospital, Zurich","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Trauma-focused Cognitive Behavioral Therapy for Children and Adolescents","TF-CBT is a child and family-focused, component-based trauma-focused intervention that aims to address post-traumatic stress symptoms and other trauma-related difficulties (e.g., anxiety, depression) associated with traumatic events.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Lasse Bartels, PhD","CONTACT","+41 44 249 56 60","lasse.bartels@kispi.uzh.ch",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"University Children's Hospital Zurich","RECRUITING","Zurich","Canton of Zurich","8008","Switzerland",{"type":27,"coordinates":28},"Point",[29,30],8.55,47.36667,{"lat":30,"lon":29},[33],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},{"type":35,"investigatorFullName":36,"investigatorTitle":37,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Lasse Bartels","Postdoctoral fellow",[39,41],{"name":40,"class":6},"Otto-Friedrich-University Bamberg",{"name":42,"class":6},"Catholic University of Eichstätt-Ingolstadt","100623903",false,"NCT07402681","Evaluating Symptom Variations and Observing Longitudinal Individual Change Effects in TF-CBT","EVOLVE","Participants will be included if:\n\n1. they are between 12 and 18 years of age;\n2. they have been exposed to at least one or more traumatic event(s) according to the DSM-5 A criteria after the age of 3 years and dating back at least 1 months (with regard to the ability of patients to remember the event(s) and to the high spontaneous remissions of PTSS in the first month after a traumatic event);\n3. they exhibit high severity of DSM-5 PTSS as indicated by a total symptom score of ≥25 assessed with the Child and Adolescent Trauma Screen 2 (CATS-2);\n4. a nonoffending adult caregiver is available for the treatment and willing to participate in weekly treatment sessions (the inclusion of a caregiver is integral to the TF-CBT treatment model);\n5. they are willing and able to attend weekly treatment sessions;\n6. if their living circumstances are safe and stable to minimize the risk of re-traumatization during the project;\n7. they and their caregiver have sufficient command of the German language (i.e., to participate in assessment \\[read\\] and treatment\\[converse\\]);\n8. they and their caregivers possess a smartphone.\n9. they and their caregiver provided written informed consent.\n\nParticipants will not be included if:\n\n1. they exhibit acute suicidal behavior or have suicidal ideations requiring immediate hospitalization;\n2. they have a documented developmental disorder (i.e., autism spectrum disorder) or current psychosis based on adolescent- and caregiver-report and clinical assessment;\n3. they exhibit severe substance misuse based on clinical assessment;\n4. take part in concurrent psychotherapy during TF-CBT;\n5. exhibit severe intellectual disability based on clinical assessment.","ALL","12 Years","18 Years",{"count":53,"type":54},21,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the level of change in post-traumatic stress symptoms in adolescents with traumatic experiences over the course of trauma-focused cognitive behavioral therapy for children and adolescents according to Cohen, Manarinno, \\& Deblinger (2017).",[58],"Post-traumatic Stress Symptoms",[60,61,62],"TF-CBT","post-traumatic stress symptoms","single-case experimental design","2026-02-04",{"date":65,"type":66},"2026-02-11","ACTUAL",{"date":68,"type":54},"2026-02",{"date":70,"type":54},"2027-12",{"name":5,"class":6},1]