[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608095":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":13,"interventions":13,"overallOfficials":13,"centralContacts":19,"locations":28,"responsibleParty":44,"collaborators":13,"id":48,"slug":13,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":13,"maxAge":13,"enrollmentInfo":56,"targetDuration":13,"studyType":59,"phases":13,"briefSummary":60,"conditions":61,"keywords":13,"overallStatus":31,"whyStopped":13,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Al-Azhar University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Modified Rankin Scale (mRS)","The mRS will be rated as follows: 0, no symptoms; 1, no substantial disability; 2, slight disability; 3, moderate disability; 4, moderately severe disability; 5, severe disability; and 6, deceased.","will be conducted on each patient on two occasions: prior to and one month subsequent to the completion of plasmapheresis.",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","PROSPECTIVE","Therapeutic plasma exchange (TPE) is recommended as Class I therapies by the American Society for Apheresis (ASFA) guidelines and are widely used as first-line therapies for the treatment of acute neuroimmune diseases , TPE is generally well tolerated, with minor complications occurring in about 20-30% of patients ,(ASFA) publishes regular guidelines on the indications for TPE. Studies performed over the last three decades showed that myasthenia gravis (MG), Guillain-Barre syndromé (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) were the most frequently cited indications for TPE followed by multiple sclerosis (MS) , The aims of this research to evaluate therapeutic plasma exchange for immune-mediated neurological diseases in a sample of Egyptian patients, including evaluating clinical response rates and functional improvement","An Experience at Al-Azhar University Hospitals (Al-Hussein \\& Sayed Galal) in Egypt",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":13,"email":24},"Wajdi Hamid Eisay, MD","CONTACT","00218911103885","wajdyessa91@gmail.com",{"name":26,"role":22,"phone":27,"phoneExt":13,"email":13},"Hussein Mohammed Hussein, Professor","00201005196285",[29],{"facility":30,"status":31,"city":32,"state":13,"zip":13,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Al-Azhar University Hospitals","RECRUITING","Cairo","Egypt","EG",{"type":36,"coordinates":37},"Point",[38,39],31.24967,30.06263,{"lat":39,"lon":38},[42],{"name":21,"role":22,"phone":43,"phoneExt":13,"email":24},"00201097429385",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"PRINCIPAL_INVESTIGATOR","Wajdi Hamid Miftah Eisay","resident","100608095",false,"NCT07197099","Evaluation for Therapeutic Plasma Exchange for Immune Mediated Neurological Disease","Evaluation of Therapeutic Plasma Exchange for Immune-Mediated Neurological Diseases in a Sample of Egyptian Patients: An Experience at Al-Azhar University Hospitals","TPE","Inclusion Criteria:\n\n* 1\\. All neurological patients irrespective of age who will undergo TPE. 2.All new and relapse cases that meet the ASFA guidelines and where TPE is the first and\u002For second line of therapy\n\nExclusion Criteria:\n\n* 1\\. Individuals with contraindications to therapeutic plasma exchange, such as hemodynamic unstable, hypocalcaemia, allergy to fresh frozen plasma or albumin.\n\n  2.Patients who will undergo fewer than five cycles of TPE and not complete the procedure.\n\n  3.Patients with non-neurological disorders.","ALL",{"count":57,"type":58},60,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to Evaluation of Therapeutic Plasma Exchange for Immune-Mediated Neurological Diseases in a Sample of Egyptian Patients: An Experience at Al-Azhar University Hospitals, including evaluating clinical response rates and functional improvement.",[62],"Neurological Autoimmune Diseases","2025-11-15",{"date":65,"type":66},"2025-11-18","ACTUAL",{"date":68,"type":66},"2025-01-01",{"date":70,"type":58},"2025-12-31",{"name":5,"class":6},1]