[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574186":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":10,"centralContacts":33,"locations":39,"responsibleParty":61,"collaborators":65,"id":81,"slug":10,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":10,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":10,"enrollmentInfo":89,"targetDuration":92,"studyType":93,"phases":10,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"preoperative group",null,"Registered liver transplant patients from preoperative to postoperative follow-up",[13,14],"Diagnostic Test: Ophthalmic examination","Diagnostic Test: General Condition Examination",{"label":16,"type":10,"description":17,"interventionNames":18},"Simple postoperative group","Follow up from after liver transplantation",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Healthy control group","Healthy individuals without liver disease",[13,14],[24,29],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"DIAGNOSTIC_TEST","Ophthalmic examination","Various ophthalmic examination modalities, including slit lamp photography, fundus photography, optical coherence tomography imaging and optical coherence tomography angiography, etc.",[20,16,9],{"type":25,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"General Condition Examination","Various general condition examination, including blood pressure measurement, blood glucose testing, blood routine examination, coagulation function test, liver function test, etc.",[20,16,9],[34],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Zizheng Cao, M.D.","CONTACT","+86-13201672078","caozzh@mail2.sysu.edu.cn",[40],{"facility":5,"status":41,"city":42,"state":43,"zip":44,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Guangzhou","Guangdong","510060","China",{"type":47,"coordinates":48},"Point",[49,50],113.25,23.11667,{"lat":50,"lon":49},[53,57],{"name":54,"role":36,"phone":55,"phoneExt":10,"email":56},"Haotian Lin, M.D., Ph.D","+86-13802793086","linht5@mail.sysu.edu",{"name":58,"role":36,"phone":59,"phoneExt":10,"email":60},"Xiaohang Wu, M.D., Ph.D","+86-15913177657","wxhang@mail2.sysu.edu.cn",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Haotian Lin","Prof.",[66,68,70,72,74,76,79],{"name":67,"class":6},"First Affiliated Hospital, Sun Yat-Sen University",{"name":69,"class":6},"Second Affiliated Hospital, Sun Yat-Sen University",{"name":71,"class":6},"Guangdong Provincial People's Hospital",{"name":73,"class":6},"Nanfang Hospital, Southern Medical University",{"name":75,"class":6},"Zhongshan People's Hospital, Guangdong, China",{"name":77,"class":78},"Guangdong Provincial People's Hospital, China","UNKNOWN",{"name":80,"class":6},"First People's Hospital of Foshan","100574186",false,"NCT06756009","Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters","Inclusion Criteria:\n\n1. Age greater than or equal to 18 years old;\n2. Late stage liver disease patients waiting for liver transplantation treatment, as well as patients with varying degrees of cirrhosis;\n3. Can collect complete basic demographic information, liver function blood test indicators, liver pathology and imaging examination results;\n4. Can cooperate with eye OCT, OCTA and other examinations, and obtain qualified examination parameters;\n5. Voluntarily follow the clinical trial protocol and sign the informed consent form.\n\nExclusion Criteria:\n\n1. History of other organ transplant surgeries;\n2. History of intraocular laser treatment, medication injection, and surgery;\n3. History of high myopia, glaucoma, and retinal choroidal related eye diseases;\n4. History of major systemic diseases other than liver disease;\n5. Individuals whose overall body and eye conditions cannot cooperate with eye examinations.",true,"ALL","18 Years",{"count":90,"type":91},500,"ESTIMATED","1 Year","OBSERVATIONAL","This study investigates the correlation between ocular biological characteristics and overall conditions before and after liver transplantation by collecting ocular biological characteristics. Explore whether it is possible to construct a clinical prediction model for liver transplantation by incorporating ocular biometric features, in order to optimize disease management before and after liver transplantation.",[96,97,98],"Diagnostic Techniques, Ophthalmological","Liver Transplantation","Liver Cirrhoses",[96,100,98],"liver transplantation","2024-12-25",{"date":103,"type":104},"2025-01-01","ACTUAL",{"date":106,"type":104},"2022-03-01",{"date":108,"type":91},"2026-12-30",{"name":5,"class":6},1]