[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100389798":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":63,"collaborators":26,"id":65,"slug":26,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":66,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vitamin D Supplement","EXPERIMENTAL","Patients will take vitamin D tablet with 4,000IU daily for 6 months.",[13],"Drug: Vitamin D 4000IU daily",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Patients will take placebo for 6 months",[19],"Drug: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Vitamin D 4000IU daily","Randomized to receive vitamin D 4000IU daily",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Randomized to placebo daily",[15],[31],{"name":32,"affiliation":5,"role":33},"Alla Vash-Margita, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","203-785-4010","alla.vash-margita@yale.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Yale New Haven Children's Hospital","RECRUITING","New Haven","Connecticut","06510","United States",{"type":48,"coordinates":49},"Point",[50,51],-72.92816,41.30815,{"lat":51,"lon":50},[54,57,61],{"name":55,"role":36,"phone":56,"phoneExt":26,"email":38},"Alla Vash-Margita, Principal Investigator, MD","203-785-7409",{"name":58,"role":36,"phone":59,"phoneExt":26,"email":60},"Kathleen Miclette, nurse coordinator, RN","203-444-3720","kathleen.miclette@ynhh.org",{"name":62,"role":33,"phone":26,"phoneExt":26,"email":26},"Alla Vash-Margita, Associate Professor, MD",{"type":64,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100389798",false,"NCT04355572","Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)","Inclusion Criteria:\n\n\\- Postmenarchal adolescent females aged 13-21 who meet modified Rotterdam criteria for PCOS, with a serum vitamin D level between 6-29 ng\u002FmL.\n\nExclusion Criteria:\n\n* Other causes for hyperandrogenism,\n* Chronic renal diseases,\n* Acquired or inherited calcium and vitamin D metabolic disorders.","FEMALE","13 Years","21 Years",{"count":74,"type":75},60,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement. Participants and investigators will be blinded to treatment modality until the end of the trial period",[81,82],"Polycystic Ovarian Syndrome in Adolescent Females","Vitamin D Deficiency",[84],"Anti-Mullerian Hormone (AMH)","2026-02-19",{"date":87,"type":88},"2026-02-23","ACTUAL",{"date":90,"type":75},"2026-05",{"date":92,"type":75},"2027-12-01",{"name":5,"class":6},1]