[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631340":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":13,"responsibleParty":32,"collaborators":7,"id":36,"slug":7,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":40,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":7,"enrollmentInfo":44,"targetDuration":7,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":7,"overallStatus":16,"whyStopped":7,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},{"fullName":5,"class":6},"Università Politecnica delle Marche","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DRUG","fluid challenge","Signs of venous congestion and microcirculatory status will be assessed at baseline. A fluid challenge will then be performed, and microcirculation will be evaluated at the end of fluid administration and again after 30 minutes",[14],{"facility":15,"status":16,"city":17,"state":18,"zip":19,"country":18,"cosmosGeoPoint":20,"geoPoint":25,"contacts":26},"AOU delle Marche","RECRUITING","Ancona","Italy","60123",{"type":21,"coordinates":22},"Point",[23,24],13.5103,43.60717,{"lat":24,"lon":23},[27],{"name":28,"role":29,"phone":30,"phoneExt":7,"email":31},"Abele Donati Pr, PhD","CONTACT","+390715963858","a.donati@univpm.it",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Abele Donati, MD","MD, PhD, Full Professor of Intensive Care, Head of the ICU","100631340",false,"NCT07499401","Evaluation of the Microcirculatory Response to Fluids in Critically Ill Patients With Venous Congestion: A Prospective Observational Study","MICRO-CONGEST","Inclusion Criteria:\n\n* Critically ill patients admitted to the intensive care unit\n* Invasive or minimally invasive hemodynamic monitoring\n\nExclusion Criteria:\n\n* Suspected or confirmed pregnancy\n* Inability to access the oral cavity (e.g., facial trauma, oral bleeding)","ALL","18 Years",{"count":45,"type":46},30,"ESTIMATED","OBSERVATIONAL","The hypothesis is that fluid-responsive patients who show signs of venous congestion experience a worsening of microcirculatory status after fluid administration compared to patients without signs of venous congestion",[50,51,52],"Venous Congestion","Microcirculation","Volume Expansion","2026-03-28",{"date":55,"type":56},"2026-04-02","ACTUAL",{"date":58,"type":56},"2024-12-15",{"date":60,"type":46},"2026-06",{"name":5,"class":6},1]