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Follow up until 2023.",{"measure":15,"description":19,"timeFrame":20},"Progression free survival","From date of diagnosis or first treatment until the date of first documented progression or date of death from any cause. Follow up until 2023.",null,{"allocation":21,"interventionModel":21,"interventionModelDescription":21,"primaryPurpose":21,"observationalModel":23,"timePerspective":24,"maskingInfo":21},"COHORT","RETROSPECTIVE","This database compiles existing data retrieved fromp patient's electronic medical records (EMR) across the 18 French comprehensive cancer centers spread over 20 sites. .\n\nThe database includes data related to patient demographics, tumor characteristics (diagnosis, histology, relapses, metastatic disease, etc.), treatments (dates, INN, route of administration, treatment protocols, reason for termination, etc.), and clinical events. Data is collected at each participating site by technicians who are specifically trained for the project using an electronic data collection (eDC) tool.\n\nData imported into the final database are controlled, recoded, and harmonized before import according to the data management plan. All coding procedures are predefined by the data manager. There is no transmission of individual data; all data are centralized within each center using a shared anonymous format. All data is exclusively obtained retrospectively; no attempts are made to recover non available data from the patient's medical record by contacting healthcare providers or patients.\n\nCases selected to enter the ESME MBC data platform fulfill specific criteria: (1) Male or female ≥18 years old (2) metastatic breast cancer (3) with first metastasis treated (either completely or partially) at a participating site from January 2008 onwards.Treatment strategies considered include radiotherapy, chemotherapy, targeted therapy and endocrine therapy.","All consecutive patients treated for a metastatic breast cancer in a French Comprehensive Cancer Center over the selection period.",[28],{"name":29,"affiliation":5,"role":30},"Lise Bosquet, MsC","STUDY_DIRECTOR",[32,35],{"name":29,"role":33,"phone":21,"phoneExt":21,"email":34},"CONTACT","l-bosquet@unicancer.fr",{"name":36,"role":33,"phone":21,"phoneExt":21,"email":37},"Mathieu Robain, MD, PhD","m-robain@unicancer.fr",[39,60,74,88,102,116,130,144,158,172,185,197,211,224,238,252,266,278,292,306],{"facility":40,"status":41,"city":42,"state":21,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Institut de Cancérologie de l'Ouest - 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Hôpital René Huguenin","Saint-Cloud","92210",{"type":47,"coordinates":271},[272,273],2.20289,48.84598,{"lat":273,"lon":272},[276],{"name":222,"role":33,"phone":277,"phoneExt":21,"email":223},"+33 1 47 11 15 15",{"facility":279,"status":41,"city":280,"state":21,"zip":281,"country":44,"countryCode":45,"cosmosGeoPoint":282,"geoPoint":286,"contacts":287},"Centre Paul Strauss","Strasbourg","67065",{"type":47,"coordinates":283},[284,285],7.74553,48.58392,{"lat":285,"lon":284},[288],{"name":289,"role":33,"phone":290,"phoneExt":21,"email":291},"Michel VELTEN","+33 3 88 25 24 53","mvelten@strasbourg.unicancer.fr",{"facility":293,"status":41,"city":294,"state":21,"zip":295,"country":44,"countryCode":45,"cosmosGeoPoint":296,"geoPoint":300,"contacts":301},"Institut Claudius Regaud","Toulouse","31059",{"type":47,"coordinates":297},[298,299],1.44367,43.60426,{"lat":299,"lon":298},[302],{"name":303,"role":33,"phone":304,"phoneExt":21,"email":305},"Delphine BERCHERY","05 31 15 50 60","Berchery.Delphine@iuct-oncopole.fr",{"facility":307,"status":41,"city":308,"state":21,"zip":309,"country":44,"countryCode":45,"cosmosGeoPoint":310,"geoPoint":314,"contacts":315},"Institut Gustave Roussy","Villejuif","94805",{"type":47,"coordinates":311},[312,313],2.35992,48.7939,{"lat":313,"lon":312},[316],{"name":317,"role":33,"phone":318,"phoneExt":21,"email":319},"Valérie DEJEAN","+33 1 42 11 46 49","valerie.dejean@gustaveroussy.fr",{"type":321,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR",[323,326,328,330,332,334,336,338,340,342],{"name":324,"class":325},"Roche Pharma AG","INDUSTRY",{"name":327,"class":325},"Pierre Fabre Laboratories",{"name":329,"class":325},"Pfizer",{"name":331,"class":325},"AstraZeneca",{"name":333,"class":325},"Merck Sharp & Dohme LLC",{"name":335,"class":325},"Eisai Inc.",{"name":337,"class":325},"Daiichi Sankyo",{"name":339,"class":325},"Eli Lilly and Company",{"name":341,"class":325},"Gilead Sciences",{"name":343,"class":325},"Seagen Inc.","100306904",false,"NCT03275311","Evolution of the Therapeutic Care in Metastatic Breast Cancer From 2008","Epidemiological Strategy and Medical Economic (ESME) Research Program \u002F Academic Real World Database: Evolution of the Therapeutic Care in Metastatic Breast Cancer Across the French Comprehensive Cancer Centers From 2008","ESME-MBC","Inclusion criteria :\n\n* 18 years old patient\n* Patient receiving chemotherapy, targeted therapy, immunotherapy, radiation therapy and hormonotherapy in a French Comprehensive Cancer Center.\n\nExclusion criteria : None","ALL","18 Years",{"count":354,"type":355},42000,"ESTIMATED","OBSERVATIONAL","The Epidemiological Strategy and Medical Economic (ESME) Breast cancer Database is a multicenter real life database using a retrospective data collection process across 18 French comprehensive cancer centers (FCCC) spread over 20 sites. This database compiles data from patient's electronic medical records (EMR).",[359],"Metastatic Breast Cancer",[361,362,363,364,365],"metastatic breast cancer","observational study","survival","real world data","real life setting","2026-05-22",{"date":368,"type":369},"2026-05-27","ACTUAL",{"date":371,"type":369},"2014-07",{"date":373,"type":355},"2027-12",{"name":5,"class":6},20]