About this trial

The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is:

• How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.

Eligibility criteria

Qualifiers

Older than 18 years

Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus.

Able to provide oral and written informed consent

Able to read and speak Danish

Disqualifiers

Prior colorectal cancer diagnosis

History of stenosis of the gastrointestinal tract

Previous treatment of inflammatory bowel disease

Previous major surgery of the gastrointesinal tract (e.g. gastric bypass)

Trial design

Treatments tested in this trial

  • Colon capsule endoscopy

Treatment groups

No treatment groups listed

Locations

1
Odense University Hospital5000, Odense Denmark

Sponsors and collaborators

Odense University Hospital

Lead sponsor