[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100439038":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":37,"responsibleParty":60,"collaborators":24,"id":62,"slug":24,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":68,"maxAge":24,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":84,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise","EXPERIMENTAL","Participants randomized to one of two groups with 2:1 ratio: exercise (n=20)\n\n\\- Aerobic and Resistance Exercise for 16 weeks",[13],"Other: Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Attention Control","ACTIVE_COMPARATOR","Participants randomized to one of two groups with attention control (n=10).\n\n-Attention Control for 16 weeks home-based stretching",[19],"Other: Attention Control",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"16-week, virtually supervised, technology-based, aerobic and resistance exercise program performed 3 days per week which starts at least 4 weeks after surgery",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Home-based stretching program consisting of one set of 4 static stretching exercises held for 30 seconds and performed 3 days\u002Fweek. Participants will be shown how to use the booklet and instructed on how to complete the stretching exercises by an exercise trainer.",[15],[29],{"name":30,"affiliation":5,"role":31},"Christina Dieli-Conwright, PhD","PRINCIPAL_INVESTIGATOR",[33],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","(617) 582-8321","ChristinaM_Dieli-Conwright@dfci.harvard.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Dana Farber Cancer Institute","RECRUITING","Boston","Massachusetts","02215","United States",{"type":46,"coordinates":47},"Point",[48,49],-71.05977,42.35843,{"lat":49,"lon":48},[52,55,59],{"name":53,"role":34,"phone":54,"phoneExt":24,"email":36},"Christina Dieli-Conwright, PhD, MPH","617-582-8321",{"name":56,"role":34,"phone":57,"phoneExt":24,"email":58},"Mary Norris, MS","857-215-0195","maryk_norris@dfci.harvard.edu",{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"type":31,"investigatorFullName":30,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Principal Investigator","100439038",false,"NCT04997096","Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy","Inclusion Criteria:\n\n* Newly diagnosed patients with stages III-IV ovarian or endometrial cancer\n* Receiving first-line carboplatin and paclitaxel chemotherapy after surgery\n* ≥18 years, children under the age of 18 will be excluded due to rarity of disease\n* Physician's clearance to participate in moderate-vigorous intensity exercise\n* Able to read, write, and understand English\n* Ability to understand and the willingness to sign an informed consent document\n* Willing to undergo two venous blood draws for the study\n\nExclusion Criteria:\n\n* Pre-existing musculoskeletal, neurological, or cardiorespiratory conditions, as determined by the treating oncologist\n* Participants with uncontrolled intercurrent illness, as determined by the treating oncologist\n* Participants with psychiatric illness\u002Fsocial situations that would limit compliance with study requirements, as determined by the treating oncologist\n* Participants who have received prior chemotherapy for cancer treatment (e.g. taxanes for breast cancer)","FEMALE","18 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer and if it will improve lower extremity function (function of the legs), lessen chemotherapy-induced peripheral neuropathy (CIPN; numbness or tingling in the hands or feet), and if there is any effect on inflammatory blood markers (the level of a certain marker in the blood that is associated with inflammation; redness and swelling).",[77,78,79,80,81,82,83],"Ovarian Cancer","Ovarian Carcinoma","Ovarian Cancer Stage IV","Ovarian Cancer Stage III","Ovarian Cancer Stage 3","Endometrial Cancer","Endometrial Cancer Stage",[77,78,79,80,81,82,85,86,87],"Aerobic Exercise","Strength Training","Cardiovascular training","2026-02-17",{"date":90,"type":91},"2026-02-19","ACTUAL",{"date":93,"type":91},"2022-04-02",{"date":95,"type":71},"2029-04-30",{"name":5,"class":6},1]