About this trial

This study aims to explore how HIIT influences brain function, neural and molecular pathways related to weight control, setting the stage for future obesity intervention research.

Eligibility criteria

Qualifiers

Age 18-70 years

Body mass index (BMI) >19 kg/m2 and body weight< 250kg

Participants must have experienced a clinically significant weight regain, defined as over 10% of their maximum weight lost, within 1 to 5 years following their bariatric surgery. They will be asked to self-report their weight loss history. Participants must also provide the operative report from their bariatric surgery for reference.

In good general health with no conditions that could influence the outcome of the trial, and in the judgment of the investigator is a good candidate for the study based on review of available medical history, physical examination and clinical laboratory evaluations

Disqualifiers

Type 1 diabetes mellitus

Peripheral neuropathy with insensate feet

Recent blood donation within the last 2 months

Use of beta-blockers

Trial design

Treatments tested in this trial

  • Exercise

Treatment groups

15 Participants
are divided into 1 treatment group

Locations

1
Joslin Diabetes Center02215, BostonMassachusetts, United States

Sponsors and collaborators

Joslin Diabetes Center

Lead sponsor

Nutrition Obesity Research Center

Collaborator