Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age21-80
SponsorMemorial Sloan Kettering Cancer Center

About this trial

This study will compare the effects on cardiorespiratory fitness (CRF) of aerobic exercise in different amounts (number of minutes/session) over different periods of time (number of weeks). Aerobic exercise is physical activity of light-to-moderate intensity that uses the large muscle groups (muscles in your legs, buttocks, back, and chest) and can be performed for at least 10 minutes.

The researchers will study the effects of different exercise programs on how well the study participants' bodies use oxygen, how well their heart pumps blood, how well their lungs function, and how healthy their blood vessels are.

Eligibility criteria

Qualifiers

Aged 21-80 years

Female

Surgically resected early stage (I-III) primary breast cancer

Age ≥ 45 with no menses for at least 2 years

Disqualifiers

Acute myocardial infarction within 3-5 days of any planned study procedures

Unstable angina

Uncontrolled arrhythmia causing symptoms or hemodynamic compromise

Recurrent syncope

Trial design

Treatments tested in this trial

  • Aerobic Training
  • Aerobic Training
  • Aerobic Training
  • Aerobic Training

Treatment groups

152 Participants
are divided into 4 treatment groups

Locations

2
Hartford Healthcare Cancer Institute @ Hartford Hospital (Data Collection Only)06102, HartfordConnecticut, United States
Memorial Sloan Kettering Cancer Center10065, New YorkNew York, United States

Sponsors and collaborators

Memorial Sloan Kettering Cancer Center

Lead sponsor

National Cancer Institute (NCI)

Collaborator