[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581601":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":19,"interventions":13,"overallOfficials":26,"centralContacts":33,"locations":13,"responsibleParty":39,"collaborators":13,"id":42,"slug":13,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":13,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":13,"maxAge":13,"enrollmentInfo":49,"targetDuration":13,"studyType":52,"phases":13,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":64,"whyStopped":13,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":13},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Factors associated with advanced HIV disease and poor nutrition among people living with HIV disease.","To study factors associated with advanced HIV disease and poor nutrition among people living with HIV","Febraury 2025 to December 2026",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"CASE_CONTROL","PROSPECTIVE","Human immunodeficiency virus (HIV) is an RNA virus that attacks the human body's immune system, which results, in advanced cases, in expression of opportunistic infections (1). HIV infection represents a global public health burden (2, 3). In Egypt, in 2022, about 34,000 people (\\\u003C0.1%) were positive for HIV (4). There is 25-30% annual increase of newly confirmed HIV cases in Egypt over the last 10 years (5).\n\nThe WHO defines advanced HIV disease as having CD4+ T-cell count \\\u003C200 cell\u002Fmm3 or having an acquired immune deficiency syndrome (AIDS)-related infection (stage 3 or 4 of HIV infection) regardless of the CD4+ T-cell count (1).\n\nThe WHO reported, in 2022, that 630,000 people living with HIV (PLWH) died from AIDS-related diseases worldwide (which is 51% fewer than those in 2010) (2, 3, 6). In Egypt, the AIDS-related deaths increased from \\\u003C100 PLWH in 1990 to \\\u003C1000 PLWH in 2021 (5).\n\nPLWH are usually malnourished due to opportunistic infections, poor food intake, changes in metabolic activity or chronic illnesses. Malnutrition leads to more impairment of the immune system and further disease progression (7).\n\nAccording to 2023 Global Hunger index, Egypt is at a moderate level of food insecurity, ranking 57 out of 125 countries. 14.4% of the Egyptian population are food insecure (8).\n\nIn Egypt, there is lack of data about the frequency of advanced HIV disease and the nutritional status among PLWH and associated factors. Monitoring these factors could help in early treatment of HIV infection, prevention of further virus transmission and enhancement of the nutritional pattern among PLWH.","People living with HIV disease who attend HIV Counselling Clinic and other departments at Assiut University Hospitals",[20,23],{"label":21,"type":13,"description":22,"interventionNames":13},"People living with Advanced HIV disease","Factors associated with advanced HIV disease",{"label":24,"type":13,"description":25,"interventionNames":13},"People with Early HIV disease","Factors associated with early HIV disease",[27,30],{"name":28,"affiliation":5,"role":29},"Haidi KaramAllah Ramadan, Assisstant professor","STUDY_DIRECTOR",{"name":31,"affiliation":5,"role":32},"Ehab Fawzy Abdou, Professor","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":13,"email":38},"Salma Hussein Badry, Resident doctor","CONTACT","+201123254745","Salma.16266321@med.aun.edu.eg",{"type":32,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Salma Hussein Badry","Doctor","100581601",false,"NCT06852430","Factors Associated With Advanced HIV and Poor Nutrition Among People Living With HIV","Factors Associated With Advanced HIV Disease and Poor Nutrition Among People Living With HIV: A Hospital-based Study","Inclusion Criteria:\n\n* (1) Newly diagnosed people living with HIV (PLWH), (2) Patients previously diagnosed with HIV but non-compliant to treatment.\n\nExclusion Criteria:\n\n* (1) PLWH compliant on ART, (2) PLWH who refuse to participate in the study","ALL",{"count":50,"type":51},100,"ESTIMATED","OBSERVATIONAL","Aim of the work:\n\n1. To determine the frequency of advanced HIV among PLWH in Assiut University Hospital.\n2. To assess the nutritional patterns and frequency of poor nutrition among PLWH.\n3. To evaluate factors associated with advanced HIV disease and poor nutrition among PLWH.",[55,56],"Advanced HIV Disease","Poor Nutriyion Among HIV Patients",[58,59,60,61,62,63],"Advanced HIV disease","AIDS","Acquired immunodeficiency syndrome","Nutrition in HIV disease","People living with HIV","PLWH","NOT_YET_RECRUITING","2025-02-25",{"date":67,"type":68},"2025-02-28","ACTUAL",{"date":70,"type":51},"2025-02-22",{"date":72,"type":51},"2027-02-01",{"name":5,"class":6}]