Health Trials

Fast Discharge After Acute Myocardial Infarction Discharge MI

ConditionAcute Myocardial Infarction (AMI)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University Innsbruck

About this trial

To evaluate the hypothesis that a fast discharge strategy (discharge at 24 \[± 12\] hours) following invasive management for acute myocardial infarction is non-inferior to standard of care (\>36 hours) with respect to the risk of major adverse cardiovascular events (MACE) during follow-up.

Eligibility criteria

Qualifiers

Uncomplicated acute myocardial infarction (NSTEMI and STEMI) diagnosed according to the 2023 acute coronary syndrome guidelines of the ESC

Age ≥ 18 years at time of consent

Invasive management strategy and in case of PCI successful intervention of the culprit lesion defined by post-interventional TIMI 3 flow

Ability to understand and willingness to sign and date written informed consent

Disqualifiers

Myocardial infarction complicated by cardiac arrest (out-of-hospital cardiac arrest/in-hospital cardiac arrest)

PCI-related complications (coronary perforation, side branch closure, inability to deliver stent/balloon, aortic dissection, allergic reaction grade ≥2, stroke/thromboembolism, access site complications including pseudoaneurysm, arteriovenous fistula, retroperitoneal hemorrhage and arterial dissection/occlusion or emboli)

Malignant arrhythmias including sustained ventricular arrhythmias and persistent bradycardia (< 50 beats per minute due to sinus node or atrioventricular conduction system abnormalities, second- /third-degree atrioventricular block) after PCI

Ongoing hemodynamic instability (systolic blood pressure <90 mmHg, elevated lactate concentrations, need for inotropes or vasopressors)

Trial design

Treatments tested in this trial

  • Fast discharge strategy

Treatment groups

2,070 Participants
are divided into 2 treatment groups

Locations

8
Austria
Hospital Wiener Neustadt2700, Wiener NeustadtLower Austria, Austria
Cardinal Schwarzenberg Hospital Schwarzach5620, Schwarzach im PongauSchwarzach Im Pongau, Austria
Paracelsus Medical University Salzburg5020, SalzburgState of Salzburg, Austria
Medical University of Graz8010, GrazStyria, Austria

Sponsors and collaborators

Medical University Innsbruck

Lead sponsor

Source ClinicalTrials.gov