[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565386":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":30,"locations":39,"responsibleParty":54,"collaborators":25,"id":57,"slug":25,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":25,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Affiliated Hospital of Jiaxing University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Guiding rehydration group","EXPERIMENTAL","According to the 421 fluid replacement principle, preoperative fluid replacement is performed",[13],"Behavioral: Guiding rehydration",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional rehydration group","ACTIVE_COMPARATOR","rehydrated within 15 minutes according to 0.2ml\u002Fkg\u002Fmin.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Guiding rehydration","Preoperative fluid rehydration was performed according to 421 fluid rehydration principles",[15,9],null,[27],{"name":28,"affiliation":5,"role":29},"Qinghe Zhou","PRINCIPAL_INVESTIGATOR",[31,35],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},"CONTACT","13732573379","jxxmxy@163.com",{"name":36,"role":32,"phone":37,"phoneExt":25,"email":38},"Xuelian Wei","18133822661","2275076157@qq.com",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":25,"country":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Affiliated Hospital of University","RECRUITING","Jiaxing","Zhejiang","China",{"type":47,"coordinates":48},"Point",[49,50],120.75,30.7522,{"lat":50,"lon":49},[53],{"name":28,"role":32,"phone":33,"phoneExt":25,"email":34},{"type":29,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Qing-he Zhou","Principal investigator","100565386",false,"NCT06641505","Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement","Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement：A Prospective, Randomized Controlled Study","Inclusion Criteria:\n\n* age over 60 years； American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ； Surgery with radial artery puncture； Propofol induction；\n\nExclusion Criteria:\n\n* BMI≥30kg\u002Fm2； People with short necks； Previous hypotension (systolic blood pressure \\\u003C90mmHg or mean arterial pressure\\\u003C65mmHg)； Previous poorly controlled hypertension； Cardiac insufficiency , EF value\\\u003C50%； Upper limb deep vein thrombosis； History of radiotherapy or neck surgery； Inability to maintain a supine position for necessary measurements； Mechanical ventilation status or inability to take deep breaths patients； gastrointestinal surgery； Patients allergic to propofol； Restricted fluid intake；","ALL","60 Years","80 Years",{"count":67,"type":68},80,"ESTIMATED","INTERVENTIONAL",[71],"NA","Compare the incidence of hypotension during the propofol-induced period between the internal jugular vein variability-guided fluid infusion group and the conventional fluid infusion group through a fluid infusion experiment before anesthesia induction, so as to evaluate the feasibility of using the internal jugular vein variability under deep inspiration to guide preoperative fluid infusion.",[74],"Hemodynamic",[76,77,78,79,80],"Internal jugular vein","propofol","hemodynamic","hypotension","fluid replacement","2024-11-13",{"date":83,"type":84},"2024-11-15","ACTUAL",{"date":86,"type":84},"2024-08-01",{"date":88,"type":68},"2025-06-01",{"name":5,"class":6},1]