[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100366130":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":37,"centralContacts":42,"locations":48,"responsibleParty":65,"collaborators":67,"id":73,"slug":21,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":21,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":21,"enrollmentInfo":81,"targetDuration":21,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":21,"overallStatus":50,"whyStopped":21,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Basic Science (microdialysis)","EXPERIMENTAL","Patients undergo microdialysis over 30 minutes during standard of care biopsy or resection.",[13,14],"Procedure: Microdialysis","Procedure: Magnetic Resonance Imaging",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"PROCEDURE","Microdialysis","Undergo microdialysis",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Magnetic Resonance Imaging","Undergo MRI",[9],[27,28,29,30,31,32,33,34,35,36],"Magnetic Resonance Imaging (MRI)","Magnetic Resonance Imaging Scan","Medical Imaging, Magnetic Resonance \u002F Nuclear Magnetic Resonance","MR","MR Imaging","NMR Imaging","Nuclear Magnetic Resonance Imaging (NMRI)","nuclear magnetic resonance imaging","sMRI","Structural MRI",[38],{"name":39,"affiliation":40,"role":41},"Terence C Burns, MD, PhD","Mayo Clinic in Rochester","PRINCIPAL_INVESTIGATOR",[43],{"name":44,"role":45,"phone":46,"phoneExt":21,"email":47},"Clinical Trials Referral Office","CONTACT","855-776-0015","mayocliniccancerstudies@mayo.edu",[49],{"facility":40,"status":50,"city":51,"state":52,"zip":53,"country":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"RECRUITING","Rochester","Minnesota","55905","United States",{"type":56,"coordinates":57},"Point",[58,59],-92.4699,44.02163,{"lat":59,"lon":58},[62,63],{"name":44,"role":45,"phone":46,"phoneExt":21,"email":47},{"name":64,"role":41,"phone":21,"phoneExt":21,"email":21},"Terence C. Burns, MD, PhD",{"type":66,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR",[68,71],{"name":69,"class":70},"National Cancer Institute (NCI)","NIH",{"name":72,"class":70},"National Institute of Neurological Disorders and Stroke (NINDS)","100366130",false,"NCT04047264","Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies","Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies","Inclusion Criteria:\n\n* Age \\>= 18 years\n* Diagnosis of the following, based on clinical and radiographic evidence:\n\n  * Any glioma\n  * Metastatic brain tumor of any primary origin\n  * Epileptic focus requiring surgical resection\n* Planned neurosurgical procedure for purposes of biopsy or resection of suspected or previously diagnosed brain tumor (primary or metastatic) or epileptic focus as part of routine clinical care\n* Willing to undergo neurosurgical resection or biopsy at Mayo Clinic (Rochester, Minnesota \\[MN\\])\n* Ability to understand and the willingness to sign a written informed consent document\n\nExclusion Criteria:\n\n* Vulnerable populations: pregnant women, prisoners or the mentally handicapped\n* Patients who are not appropriate candidates for surgery due to current or past medical history or uncontrolled concurrent illness","ALL","18 Years",{"count":82,"type":83},100,"ESTIMATED","INTERVENTIONAL",[86],"NA","This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intraoperative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors to develop new strategies to better diagnose, monitor, and treat brain tumors.",[89,90,91],"Glioma","Glioblastoma","Metastatic Malignant Neoplasm in the Brain","2026-02-10",{"date":94,"type":95},"2026-02-12","ACTUAL",{"date":97,"type":95},"2020-01-01",{"date":99,"type":83},"2027-09-01",{"name":5,"class":6},1]