Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Michigan
About this trial
The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut microbiome. The study team also wants to understand if adding potato starch to participant's diet helps these bacteria make more short chain fatty acids, a byproduct the team thinks may benefit participant's health.
Eligibility criteria
Qualifiers
A confirmed clinical diagnosis of stable HFpEF on maximally tolerated Heart Failure (HF) medical regimen (without changes in dosage in the prior month)
Left ventricular ejection fraction of >50% documented in the prior 12 months
A confirmed clinical diagnosis of Type II diabetes (T2DM) with glycated hemoglobin <10% without changes in medical regimen in the past month.
Disqualifiers
Current usage of pre- or probiotic usage
Antibiotic usage in the past 6 months
Current participation in another interventional clinical trial
History of potato allergy or potato starch allergy, inflammatory bowel syndrome, inflammatory bowel disease, bowel resection, Roux-en-Y gastric bypass surgery, celiac disease, Crohn's disease, or colorectal cancer
Trial design
Treatments tested in this trial
- Potato Starch
Treatment groups
30 Participants
are divided into 1 treatment groupLocations
1University of Michigan48109, Ann ArborMichigan, United States
Sponsors and collaborators
University of Michigan
Lead sponsor
Source ClinicalTrials.gov