[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526385":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":26,"responsibleParty":46,"collaborators":48,"id":55,"slug":26,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":26},{"fullName":5,"class":6},"Vestre Viken Hospital Trust","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"55% correction","EXPERIMENTAL","HTO using PSI targeted at 55% correction axis",[13],"Procedure: Procedure: HTO using PSI aiming at 55% correction",{"label":15,"type":16,"description":17,"interventionNames":18},"62% correction","ACTIVE_COMPARATOR","HTO using PSI targeted at 62% correction axis",[19],"Procedure: Procedure: HTO using PSI aiming at 62% correction",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Procedure: HTO using PSI aiming at 55% correction","HTO using PSI designed to achieve correction to 55% tibial width.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Procedure: HTO using PSI aiming at 62% correction","HTO using PSI designed to achieve correction to 62% tibial width.",[15],[32],{"name":33,"affiliation":34,"role":35},"Tor Kjetil Nerhus, MD, PhD","Martina Hansens Hospital","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Geir Solberg, MD","CONTACT","+4746821397","geir.solberg@mhh.no",{"name":43,"role":39,"phone":44,"phoneExt":26,"email":45},"Tor Kjetil Nerhus, MD,PhD","+4793409934","kjetil.nerhus@mhh.no",{"type":47,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[49,51,53],{"name":50,"class":6},"South-Eastern Norway Regional Health Authority",{"name":52,"class":6},"Oslo University Hospital",{"name":54,"class":6},"Lovisenberg Diakonale Hospital","100526385",false,"NCT06134050","Finding the Optimal Aim of Correction in Opening Wedge High Tibial Osteotomy","Finding the Optimal Aim of Correction in Opening Wedge High Tibial Osteotomy Using 3D Printed Patient-specific Instrumentation (PSI). An RCT Comparing Correction Aimed at 62% Versus 55%.","Inclusion Criteria:\n\n* Patients having accepted and signed the informed consent form before surgery\n* Patients aged 30-60 years\n* Patients with an indication for primary HTO based on anamnestic, clinical and radiological findings leading to the diagnosis of major medial knee compartment overload symptoms\n* Mechanical varus axis of 3-9 deg. (calculated on full length weightbearing X-ray (FLWB))\n* Correctable angular deformity on the tibia only (medial proximal tibial angle (MPTA) + planned correction \\\u003C 95 deg. Lateral distal femoral angle (LDFA) \\\u003C92 deg.)\n* Maximal calculated gap height 14 mm\n* Only the first knee will be included if later contralateral HTO\n\nExclusion Criteria:\n\n* Inflammatory arthritis (Rheumatoid Arthritis, Bechterew arthritis, Psoriatic Arthritis)\n* Patients using Prednisolone perorally\n* Smokers (need to quit preoperatively)\n* Significant overweight (Body Mass Index \\> 35)\n* Earlier fractures in affected leg with fracture malalignment \\>5 deg.\n* Extension deficit \\>10 deg. in the affected knee\n* Earlier septic arthritis\u002Fosteomyelitis in the affected leg\n* Previous major surgery affecting leg function. Earlier knee arthroscopic procedures like ACL-reconstruction are not excluded\n* Planned combined procedures involving HTO + ACL\u002FPCL-reconstruction, meniscal transplantation or meniscal root fixation is excluded\n* Neurologic disease with symptoms affecting the leg\n* Serious illness or other factors that make communication, follow-up or rehabilitation difficult (e.g. alcohol or drug abuse, psychiatric disease, non-Norwegian speakers).","ALL","20 Years","60 Years",{"count":65,"type":66},70,"ESTIMATED","INTERVENTIONAL",[69],"NA","The purpose of this RCT is to investigate whether high tibial osteotomy using 3D printed patient specific guides aiming at 55% correction is non-inferior to aiming at 62%.",[72,73,74],"Osteoarthritis, Knee","Knee Pain Chronic","Arthralgia",[76,77,78,79,80,81,82,83,84,85,86,87],"osteotomy","knee","osteoarthritis","3D print","PSI","High tibial osteotomy","Knee overload","Inertial measurement units","IMU","wearable sensors","gait analysis","accelerometer","NOT_YET_RECRUITING","2023-11-10",{"date":91,"type":92},"2023-11-18","ACTUAL",{"date":94,"type":66},"2023-11",{"date":96,"type":66},"2028-10",{"name":5,"class":6}]