About this trial

This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))

Eligibility criteria

Qualifiers

Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant

8-25 years old

Height: ≥ 48 inches

Ambulatory without assistance

Disqualifiers

ALL specific: received cranial radiation, bone marrow transplant recipients

Investigator or patient's primary physician deems the patient unsuitable for the study

History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function

Investigator deems the patient unsuitable for the study

Trial design

Treatments tested in this trial

  • Physical activity

Treatment groups

90 Participants
are divided into 2 treatment groups

Locations

1
Masonic Cancer Center55455, MinneapolisMinnesota, United States

Sponsors and collaborators

Masonic Cancer Center, University of Minnesota

Lead sponsor