About this trial

One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.

Eligibility criteria

Qualifiers

Adults (≥ 18 years old)

Patients intubated and undergoing one-lung ventilation during thoracic surgery

Volume-controlled ventilation mode used intraoperatively

Disqualifiers

Arterial blood gas data unavailable during one-lung ventilation

Missing demographic data (sex, height, actual weight)

Trial design

Treatments tested in this trial

  • one lung ventilation

Treatment groups

100 Participants
are divided into 1 treatment group

Locations

1
Institut universitaire de cardiologie et de pneumologie de Québec - Université LavalG1V4G5, QuébecQuebec, Canada

Sponsors and collaborators

Laval University

Lead sponsor