[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581663":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":28,"responsibleParty":66,"collaborators":70,"id":73,"slug":10,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":10,"enrollmentInfo":83,"targetDuration":10,"studyType":86,"phases":10,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy",null,"Community-dwelling older adults (≥60 years) with no recent hospitalization",{"label":13,"type":10,"description":14,"interventionNames":10},"ICU Survivor","Patients who survived ICU admission for ARF or sepsis in the last year",{"label":16,"type":10,"description":17,"interventionNames":10},"Chronic Pulmonary Disease","Community-dwelling adults with diagnosis of COPD, ILD, or PF",[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Research Associate Senior","CONTACT","859-323-5438","delong2@uky.edu",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Primary Investigator","859-218-0596","kpmaye2@uky.edu",[29,50],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Florida Atlantic University","RECRUITING","Boca Raton","Florida","33431","United States",{"type":37,"coordinates":38},"Point",[39,40],-80.0831,26.35869,{"lat":40,"lon":39},[43,47],{"name":44,"role":21,"phone":45,"phoneExt":10,"email":46},"Principal Investigator","(561) 297-2938","aartese@fau.edu",{"name":48,"role":49,"phone":10,"phoneExt":10,"email":10},"Ashley Artese, PhD","PRINCIPAL_INVESTIGATOR",{"facility":51,"status":31,"city":52,"state":53,"zip":54,"country":35,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Duke University","Durham","North Carolina","27708",{"type":37,"coordinates":56},[57,58],-78.89862,35.99403,{"lat":58,"lon":57},[61,64],{"name":44,"role":21,"phone":62,"phoneExt":10,"email":63},"919-681-3595","amy.pastva@duke.edu",{"name":65,"role":49,"phone":10,"phoneExt":10,"email":10},"Amy Pastva, PT, MA, PhD",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Kirby Mayer","Associate Professor",[71,72],{"name":51,"class":6},{"name":30,"class":6},"100581663",false,"NCT06853236","Functional Incremental Stepping in Place Test (F-IST) Validation","A Cardiorespiratory Fitness Test for Acute Illness: Validity, Reliability, and Clinical Utility of Functional Incremental Stepping-in-Place Test","F-IST","Inclusion Criteria:\n\n-Currently able to walk with or without a walking aid, such as a cane or walker or rollator\n\nExclusion Criteria:\n\nPregnancy\n\nspecifically related to cardiopulmonary testing\n\n* A recent significant change in resting ECG\n* Unstable angina\n* Uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise\n* Symptomatic severe aortic stenosis\n* Uncontrolled symptomatic heart failure\n* Acute pulmonary embolus or pulmonary infarction\n* Acute myocarditis or pericarditis\n* Suspected or known dissecting aneurysm\n* Acute systemic infection accompanied by fever, body aches, or swollen lymph glands\n* Left Main Coronary Stenosis\n* Moderate stenotic valvular heart disease\n* Electrolyte abnormalities\n* Severe arterial hypertension (\\>200 systolic, \\>110 diastolic) at rest\n* Tachydysrhythmia or bradydysrhythmia\n* Hypertrophic cardiomyopathy and other forms of outflow tract obstruction\n* Neuromuscular, musculoskeletal, or rheumatic disorders that are exacerbated by exercise\n* High degree AV block\n* Ventricular aneurysm\n* Uncontrolled metabolic disease (diabetes, thyrotoxicosis, or myxedema)\n* Chronic infectious disease (hepatitis, AIDS, mono)\n* Mental or physical impairment leading to inability to exercise adequately",true,"ALL","18 Years",{"count":84,"type":85},60,"ESTIMATED","OBSERVATIONAL","The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to physical function and health perception, respectively. The investigators will also assess test-retest reliability of the F-IST. The investigators hypothesize that the F-IST will have high validity and test-retest reliability to be used in field testing environments such as the ICU.",[89,90],"Intensive Care Medicine","Acute Care Medical",[92,93,94,95,96,97],"Cardio respiratory fitness","incremental step test","validity","reliability","physical function","graded exercise testing","2026-03-16",{"date":100,"type":101},"2026-03-17","ACTUAL",{"date":103,"type":101},"2024-07-02",{"date":105,"type":85},"2026-07-02",{"name":68,"class":6},2]