[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578991":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":11,"centralContacts":39,"locations":11,"responsibleParty":49,"collaborators":11,"id":51,"slug":11,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":11,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":73,"whyStopped":11,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":11},{"fullName":5,"class":6},"Beijing Tongren Hospital","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Ganyan1","EXPERIMENTAL",null,[13,14],"Drug: Ganyan1","Drug: Sodium Hyaluronate",{"label":16,"type":10,"description":11,"interventionNames":17},"1\u002F2Ganyan1",[14,18],"Drug: 1\u002F2Ganyan1",{"label":20,"type":21,"description":11,"interventionNames":22},"Placebo","PLACEBO_COMPARATOR",[14,23],"Drug: Placebo",[25,29,33,36],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":11},"DRUG","During the treatment period, participants will receive the following Chinese herbal granules, including Chrysanthemum, Dendrobium, Salvia miltiorrhiza, Gypsum Fibrosum, and Goji berries, administered twice daily at a dose of 10 g per time for a duration of 4 weeks.",[9],{"type":26,"name":30,"description":31,"armGroupLabels":32,"otherNames":11},"Sodium Hyaluronate","Participants received 0.1% sodium hyaluronate eye drop",[16,9,20],{"type":26,"name":16,"description":34,"armGroupLabels":35,"otherNames":11},"During the treatment period, participants will receive the following Chinese herbal granules, including Chrysanthemum, Dendrobium, Salvia miltiorrhiza, Gypsum Fibrosum, and Goji berries, administered twice daily at a dose of 5 g per time for a duration of 4 weeks.",[16],{"type":26,"name":20,"description":37,"armGroupLabels":38,"otherNames":11},"Participants will receive the following placebo Chinese herbal granules, administered twice daily at a dose of 10 g per time for a duration of 4 weeks.",[20],[40,45],{"name":41,"role":42,"phone":43,"phoneExt":11,"email":44},"Dong Wu, Doctor","CONTACT","8613810988682","wudong0120@outlook.com",{"name":46,"role":42,"phone":47,"phoneExt":11,"email":48},"Haihong Lian, Doctor","8618811612190","lianhh123@163.com",{"type":50,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100578991",false,"NCT06818487","Ganyan-1 in Dry Eye","Ganyan-1 in Dry Eye: A Randomized Clinical Trial","Inclusion Criteria:\n\n1\\. Age \\>=18 and Age \\\u003C=70, complaint of DED symptoms for 6 months or longer at screening.\n\n3\\. ocular surface disease index (OSDI) score of 25 or higher. 4. tear film breakup time (TFBUT) of 5 seconds or less. 5. Schirmer I test without anesthesia of 5 mm or more at 5 minutes. 6. CFS score of 4 or higher.\n\nExclusion Criteria:\n\n1. History systemic autoimmune diseases and ocular\u002Fperiocular malignancy.\n2. Clinically relevant slitlamp findings or abnormal lid anatomy.\n3. Active ocular allergies and active infection.\n4. Pregnant or lactating women.","ALL","18 Years","70 Years",{"count":61,"type":62},219,"ESTIMATED","INTERVENTIONAL",[65],"NA","Ganyan -1 for the patients with dry eye",[68,69],"Dry Eye","TCM",[71,69,72],"Dry eye","RCT","NOT_YET_RECRUITING","2025-06-19",{"date":76,"type":77},"2025-06-25","ACTUAL",{"date":79,"type":62},"2025-07-01",{"date":81,"type":62},"2027-02-01",{"name":5,"class":6}]