[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553200":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":21,"studyPopulation":22,"armGroups":23,"interventions":33,"overallOfficials":17,"centralContacts":39,"locations":45,"responsibleParty":65,"collaborators":17,"id":69,"slug":17,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":17,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":81,"studyType":82,"phases":17,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":48,"whyStopped":17,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Umraniye Education and Research Hospital","OTHER_GOV",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"intraocular pressure during genel anesthesia","intraocular pressure (mmHg)","through study completion, an average of 1 day",[14],{"measure":15,"description":16,"timeFrame":12},"hemodynamic data","mean arterial pressure (mmHg)",null,{"allocation":17,"interventionModel":17,"interventionModelDescription":17,"primaryPurpose":17,"observationalModel":19,"timePerspective":20,"maskingInfo":17},"COHORT","PROSPECTIVE","Cataract stands as a significant cause of vision impairment worldwide, notably prevalent among the elderly. This study aims to explore the changes in intraocular pressure (IOP) and blood pressure under general anesthesia during cataract surgery in frail geriatric patients. The research emphasizes the critical role of frailty assessment in determining surgical risks among elderly surgical patients. It focuses on the hypothesis that frail individuals undergoing cataract surgery under general anesthesia might experience more pronounced effects on IOP and blood pressure during the surgical procedure compared to prefrail counterparts. This study emerges as a crucial step in understanding the impact of preoperative frailty assessment on surgical planning and outcomes.","This prospective randomized controlled double-blind study included a total of 80 ASA I-III patients aged 65-85 years undergoing cataract surgery under general anesthesia. Randomization Patients were randomly divided into two groups with frailty score as non-frail (40 patients) and pre-frail\u002Ffrail (40 patients) by closed envelope method.",[24,29],{"label":25,"type":17,"description":26,"interventionNames":27},"group A","Frail scale:Non frail",[28],"Other: Intraocular pressure (IOP) was measured",{"label":30,"type":17,"description":31,"interventionNames":32},"group B","Frail scale: Pre frail\u002Ffrail",[28],[34],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":17},"OTHER","Intraocular pressure (IOP) was measured","The Frail Scale was used to assess the frailty of the patients.Intraocular pressure (IOP) was measured before anesthesia, 5 minutes after induction of anesthesia and 1 hour postoperatively. IOP was measured using a Tono-pen tonometer (AccuPen). The normal range of IOP is 11-21 mmHg (mean 16 mmHg) and values above 24 mmHg are pathologic.",[25,30],[40],{"name":41,"role":42,"phone":43,"phoneExt":17,"email":44},"zeliha tuncel","CONTACT","05053577483","zelihalara@yahoo.com",[46],{"facility":47,"status":48,"city":49,"state":17,"zip":50,"country":51,"countryCode":17,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Umraniye Education and Research hospital","RECRUITING","Istanbul","34764","Turkey (Türkiye)",{"type":53,"coordinates":54},"Point",[55,56],28.94966,41.01384,{"lat":56,"lon":55},[59,62],{"name":60,"role":42,"phone":61,"phoneExt":17,"email":44},"Zeliha Tuncel","0216 632 18 18",{"name":63,"role":42,"phone":61,"phoneExt":17,"email":64},"Duygu Harika Ozer","harikaduyguozer@gmail.com",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Zeliha Alicikus","head of Anesthesia and reanimation","100553200",false,"NCT06482996","General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery","the Impact of General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery","Inclusion Criteria:\n\n* 65-85 age\n* ASA I-III\n* cataract surgery with genel anesthesia\n\nExclusion Criteria:\n\n* cerebrovascular disease,\n* mental retardation and psychiatric illness,\n* pulmonary infection, history of advanced COPD or respiratory failure,\n* EF less than 40%, presence of cardiovascular disease,\n* bleeding diathesis,\n* renal and hepatic insufficiency,\n* presence of diabetes mellitus, diuretic\u002Fmannitol users,\n* substance abuse\n* BMI \\>30","ALL","65 Years","85 Years",{"count":79,"type":80},80,"ESTIMATED","1 Day","OBSERVATIONAL","The primary aim of the study is to investigate the correlation between preoperative hemodynamics and frailty scores in patients undergoing cataract surgery under general anesthesia. The secondary objective is to explore the relationship between preoperative and postoperative intraocular pressure changes and frailty scores.",[85],"Cataract",[87,88],"Cataract surgery","Frailty","2025-11-16",{"date":91,"type":92},"2025-11-19","ACTUAL",{"date":94,"type":92},"2023-10-20",{"date":96,"type":80},"2026-02-27",{"name":5,"class":6},1]