[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100543264":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":21,"responsibleParty":38,"collaborators":7,"id":40,"slug":7,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":7,"eligibilityCriteria":44,"healthyVolunteers":41,"sex":45,"minAge":46,"maxAge":7,"enrollmentInfo":47,"targetDuration":7,"studyType":50,"phases":7,"briefSummary":51,"conditions":52,"keywords":7,"overallStatus":24,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Denis Berdajs, Prof. Dr.","PRINCIPAL_INVESTIGATOR",[13,17],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","0041 61 328 71 80","denis.berdajs@usb.ch",{"name":18,"role":14,"phone":19,"phoneExt":7,"email":20},"Islam Salikhanov, Dr.","0041 61 26 53225","Islam.Salikhanov@usb.ch",[22],{"facility":23,"status":24,"city":25,"state":7,"zip":26,"country":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"University Hospital Basel","RECRUITING","Basel","4031","Switzerland",{"type":29,"coordinates":30},"Point",[31,32],7.57327,47.55839,{"lat":32,"lon":31},[35,36],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},{"name":18,"role":14,"phone":19,"phoneExt":7,"email":37},"islam.salikhanov@usb.ch",{"type":39,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100543264",false,"NCT06353607","Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.","Inclusion Criteria:\n\n* All adult patients \\> 18 years who underwent surgery for aAD or TAA intervention at the University Hospital Basel, starting in 2015.\n* All patients who will undergo surgery for aAD or TAA at the University Hospital Basel, beginning in 2024.\n\nExclusion Criteria:\n\n* Patients will be excluded if they are not able or not willing to provide informed consent.\n* Patients with diagnosed heritable vascular disorders, such as Marfan syndrome, Turner Syndrome, Loeyes Dietz and Ehlers-Danlos syndrome.","ALL","18 Years",{"count":48,"type":49},730,"ESTIMATED","OBSERVATIONAL","The aim of this study is to explore the genetic information associated with the development of TAA and aAD in individuals without history or syndromic features (Marfan syndrome, Ehlers-Danlos syndrome, Turner syndrome etc.) for aortic disease. For this purpose, whole genome sequencing will be performed in patients with documented aortic aneurysm or\u002Fand aortic dissection.",[53,54],"Acute Aortic Dissection","Thoracic Aortic Aneurysm","2025-05-15",{"date":57,"type":58},"2025-05-16","ACTUAL",{"date":60,"type":58},"2024-04-08",{"date":62,"type":49},"2028-12-31",{"name":5,"class":6},1]