About this trial

The goal of this observational study is to learn about the genetic insights of arrhythmya-induced cardiomyopathy and its clinical prognosis. The main questions it aims to answer are:

I. Does patients with arrhythmia-induced cardiomyopathy have a greater proportion of genetic mutations compared with other types of cardiomyopathy or general population? II. Have the genetics any prognostic impact in patients with arrhythmia-induced cardiomyopathy?

Eligibility criteria

Qualifiers

Presence of atrial fibrillation or atrial flutter not self-limited.

Performance of a cardiac imaging test with systolic function analysis (echocardiogram, magnetic resonance, CT scan) during the clinical course of the arrhythmia, exhibiting a left ventricular ejection fraction (LVEF) <50%. In order for the test to be representative, the maximum time between the performance of the imaging test and the rhythm control procedure will be 3 months, in the absence of intervening cardiovascular events that may have caused a variation in LVEF. In the event that the patient had a previously known LVEF <50%, the change with respect to this attributable to tachyarrhythmia has to be ≥10%.

Signature of informed consent.

Ability to understand and accept participation in the study.

Disqualifiers

Refusal of informed consent.

Legal or juridical incapacity.

Age <18 years.

Life expectancy less than 1 year.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

109 Participants
are grouped into 2 trial groups

Locations

4
Ciudad Real General University Hospital15004, Ciudad RealCastille-La Mancha, Spain
12 de Octubre University Hospital28004, MadridMadrid, Spain
Albacete University Hospital Complex Albacete Spain
Ramón y Cajal University Hospital Madrid Spain

Sponsors and collaborators

Hospital Universitario 12 de Octubre

Lead sponsor