[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605147":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":84,"collaborators":26,"id":86,"slug":26,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":26,"eligibilityCriteria":91,"healthyVolunteers":87,"sex":92,"minAge":93,"maxAge":26,"enrollmentInfo":94,"targetDuration":26,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Genicular Nerve Block","EXPERIMENTAL","This arm of patients (17 total) will receive the genicular nerve block for their knee pain.",[13],"Procedure: Genicular nerve block with bupivacaine and corticosteroids",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of Care","ACTIVE_COMPARATOR","This arm of patients (17 total) will receive standard of care analgesia for their knee pain",[19],"Other: Standard of Care",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Genicular nerve block with bupivacaine and corticosteroids","genicular nerve block with ideal body-weight dosing of bupivacaine 0.5% with 4 mg dexamethasone",[9],null,{"type":6,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"This involves standard of care pain relief for patients who do not receive the genicular nerve block for knee pain, such as acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and opioids.",[15],[31],{"name":32,"affiliation":5,"role":33},"Michael M Shalaby, MD","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Umar Clinical Research Coordinator, AB","CONTACT","267-624-4394","umar.aulia@pennmedicine.upenn.edu",[41,59,67,75],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Hospital of the University of Pennsylvania","RECRUITING","Philadelphia","Pennsylvania","19104","United States",{"type":49,"coordinates":50},"Point",[51,52],-75.16362,39.95238,{"lat":52,"lon":51},[55,58],{"name":56,"role":37,"phone":38,"phoneExt":26,"email":57},"Michael Shalaby, MD","michael.shalaby@pennmedicine.upenn.edu",{"name":56,"role":33,"phone":26,"phoneExt":26,"email":26},{"facility":60,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"Pennsylvania Hospital",{"type":49,"coordinates":62},[51,52],{"lat":52,"lon":51},[65,66],{"name":56,"role":37,"phone":38,"phoneExt":26,"email":57},{"name":56,"role":33,"phone":26,"phoneExt":26,"email":26},{"facility":68,"status":43,"city":44,"state":45,"zip":46,"country":47,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"Pennsylvania Presbyterian Medical Center",{"type":49,"coordinates":70},[51,52],{"lat":52,"lon":51},[73],{"name":74,"role":37,"phone":38,"phoneExt":26,"email":57},"Michael Shalaby",{"facility":76,"status":43,"city":44,"state":45,"zip":77,"country":47,"cosmosGeoPoint":78,"geoPoint":80,"contacts":81},"HUP Cedar","19143",{"type":49,"coordinates":79},[51,52],{"lat":52,"lon":51},[82,83],{"name":56,"role":37,"phone":38,"phoneExt":26,"email":57},{"name":56,"role":33,"phone":26,"phoneExt":26,"email":26},{"type":85,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100605147",false,"NCT07158736","Genicular Nerve Block for Knee Pain in the ED","Ultrasound-Guided Genicular Nerve Block for Knee Pain in the Emergency Department: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Atraumatic knee pain\n* \\>17 years age\n* X-ray of the knee obtained in the ED\n* Initial pain score (numeric rating scale) 5-10\n\nExclusion Criteria:\n\n* Fracture or dislocation on x-ray\n* large knee joint effusion identified on x-ray\n* allergy or contraindication to local anesthetics\n* History of local anesthetic systemic toxicity after receiving local anesthetics\n* Pregnancy\n* Incarcerated\n* History of knee replacement of affected knee\n* Concern for septic joint\n* Overlying cellulitis\n* Hemodynamic instability\n* Altered mental status or inability to consent for procedure.","ALL","18 Years",{"count":95,"type":96},34,"ESTIMATED","INTERVENTIONAL",[99],"NA","Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.",[102],"Knee Pain","2026-02-11",{"date":105,"type":106},"2026-02-12","ACTUAL",{"date":108,"type":106},"2025-08-06",{"date":110,"type":96},"2026-09-01",{"name":5,"class":6},4]