[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100519349":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":19,"interventions":29,"overallOfficials":35,"centralContacts":40,"locations":52,"responsibleParty":70,"collaborators":73,"id":77,"slug":13,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":13,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":13,"maxAge":13,"enrollmentInfo":84,"targetDuration":13,"studyType":87,"phases":13,"briefSummary":88,"conditions":89,"keywords":13,"overallStatus":54,"whyStopped":13,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Mount Sinai Hospital, Canada","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Genomics studies across populations","Whole Exome Sequencing (+\u002F- other sequencing) is planned","2022-2027",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"CASE_CONTROL","PROSPECTIVE","Background:\n\nInflammatory bowel disease (IBD) is a chronic, and often disabling, disorder of the intestines characterized by dysregulation of mucosal immune response. Recent data suggests that the incidence and prevalence rates among all populations may be increasing due to constantly changing environmental exposures. The goal of the study is to identify susceptible genes that contribute to the pathogenesis of IBD in affected individuals.","IBD or Healthy controls (non-IBD)",[20,25],{"label":21,"type":13,"description":22,"interventionNames":23},"IBD Subjects","Available medical records to confirm IBD diagnosis (Crohn's disease, Ulcerative colitis, IBD undetermined (IBD-U)) Any age Willing to provide blood or saliva sample",[24],"Genetic: Blood or saliva sample collection",{"label":26,"type":13,"description":27,"interventionNames":28},"Controls","No personal history of IBD, no family history of IBD, no history of unexplained chronic diarrhea\u002Fblood in stool\u002Fanemia\u002Fabdominal pain\u002Fweight loss Any age Willing to provide blood or saliva sample",[24],[30],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":13},"GENETIC","Blood or saliva sample collection","Blood or saliva sample \\& clinical data collection",[26,21],[36],{"name":37,"affiliation":38,"role":39},"Mark Silverberg, MD PhD","Sinai Health System","PRINCIPAL_INVESTIGATOR",[41,47],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},"Joanne Stempak, MSc","CONTACT","4165864800","8399","joanne.stempak@sinaihealth.ca",{"name":48,"role":43,"phone":49,"phoneExt":50,"email":51},"Jenny Lee, MKin","416-586-4800","2318","jenny.lee2@sinaihealth.ca",[53],{"facility":38,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"RECRUITING","Toronto","Ontario","M5G 1X5","Canada","CA",{"type":61,"coordinates":62},"Point",[63,64],-79.39864,43.70643,{"lat":64,"lon":63},[67,68],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},{"name":48,"role":43,"phone":44,"phoneExt":50,"email":69},"IBD.research@sinaihealth.ca",{"type":39,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Mark Silverberg","Dr.",[74],{"name":75,"class":76},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100519349",false,"NCT06042387","Genome Analysis Across Populations in Inflammatory Bowel Disease","Inclusion Criteria:\n\n* Subjects: diagnosed with Inflammatory Bowel Disease (Crohn's disease, ulcerative colitis, IBD-undetermined)\n* Available medical records to confirm IBD diagnosis (Crohn's disease, Ulcerative colitis, IBD undetermined (IBD-U))\n* Healthy controls: no personal history of IBD, no family history of IBD, no history of unexplained chronic diarrhea\u002Fblood in stool\u002Fanemia\u002Fabdominal pain\u002Fweight loss\n* Any age\n\nExclusion Criteria:\n\n\\- Subjects with other gastrointestinal conditions not meeting the above IBD or Healthy Control criteria",true,"ALL",{"count":85,"type":86},150,"ESTIMATED","OBSERVATIONAL","Objective:\n\nTo use clinical, genetic and genome analysis to better understand and define the genetic and environmental factors that contribute to IBD within affected populations.",[90,91,92,93],"Ulcerative Colitis","Healthy","Crohn Disease","Inflammatory Bowel Diseases","2025-03-20",{"date":96,"type":97},"2025-03-25","ACTUAL",{"date":99,"type":97},"2022-05-01",{"date":101,"type":86},"2027-09",{"name":5,"class":6},1]