About this trial
To date, more than 300 patients have been treated with Glofitamab in the Expanded Access Programme (EAP) in France. In this study, it is proposed to perform a retrospective analysis of some of these patients. The aim is to describe the efficacy and safety of Glofitamab in the largest reported real-world cohort, with an expected median follow-up of more than 9 months. Particular focus will be given to the relapsed or refractory chimeric antigen receptors-T (CAR-T) population to confirm the response rates (CRR: 35-39%) of Glofitamab in this population and to assess the optimal timing of therapy initiation \[8, 15\].
Eligibility criteria
Qualifiers
patient enrolled in the French Glofitamab EAP for R/R DLBCL before 2024 November 1st, 2024
patient who received at least Obinutuzumab pretreatment and one infusion of Glofitamab
adult patient
patient who is informed of the study and who did not oppose to their data collection
Disqualifiers
none
Trial design
Treatments tested in this trial
- Glofitamab
Treatment groups
Locations
30Sponsors and collaborators
The Lymphoma Academic Research Organisation
Lead sponsor