[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100377980":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":51,"collaborators":54,"id":59,"slug":10,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":10,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":10,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":80,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8],{"label":9,"type":10,"description":9,"interventionNames":11},"Middle-aged and Older adults with Prediabetes",null,[12],"Device: Continuous Glucose Monitoring System (CGMS)",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","Continuous Glucose Monitoring System (CGMS)","Continuous Glucose Monitoring System (CGMS)- minimally invasive sensors that measure glucose concentrations at 5-min intervals over several days.",[9],[20],{"name":21,"affiliation":22,"role":23},"Tasneem Khambaty, PhD","University of Maryland, Baltimore County","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Kathleen Simpson","CONTACT","4106057179","Kathleen.Simpson@va.gov",{"name":31,"role":27,"phone":10,"phoneExt":10,"email":32},"Ashley Splain, BA","asplain1@umbc.edu",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Baltimore VA Geriatric Research Education and Clinical Center (GRECC)","RECRUITING","Baltimore","Maryland","21201","United States",{"type":42,"coordinates":43},"Point",[44,45],-76.61219,39.29038,{"lat":45,"lon":44},[48],{"name":21,"role":27,"phone":49,"phoneExt":10,"email":50},"410-455-2304","khambaty@umbc.edu",{"type":23,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Leslie Katzel","Associate Professor",[55,58],{"name":56,"class":57},"Baltimore VA Medical Center","FED",{"name":22,"class":6},"100377980",false,"NCT04201600","Glucose Variability and Cognition in Prediabetes","Relations of Glucose Variability with Cognitive Function and Functional Status Among Older Adults At Risk for Diabetes","Inclusion Criteria:\n\n* Aged 50 years and older\n* At least 8th grade education\n\nExclusion Criteria:\n\n* Diagnosed type 1 or type 2 diabetes\n* Current use of mediation for diabetes (oral hypoglycemic agents, insulin), or with diabetic properties (e.g., steroids)\n* Chronic disorders (cardiovascular disease, peripheral vascular disease, stroke, transient ischemic attack, chronic kidney disease, past year cancer)\n* Neurological disorders (e.g., Parkinson's, epilepsy, multiple sclerosis)\n* History of dementia or suspected dementia\n* Known HIV\n* Serious mental illness, psychosis, or use of psychotropic medication\n* Heavy alcohol use",true,"ALL","50 Years",{"count":69,"type":70},30,"ESTIMATED","OBSERVATIONAL","This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.",[74,75,76,77,78,79],"Glucose Metabolism Disorders (Including Diabetes Mellitus)","Cognitive Decline","Functional Status","PreDiabetes","Aging","Depression",[81,16,82,78,83,84,75],"Glucose Variability","Prediabetes","Physical Functioning","Neurocognition","2025-03-25",{"date":87,"type":88},"2025-03-30","ACTUAL",{"date":90,"type":88},"2022-03-01",{"date":92,"type":70},"2026-12-31",{"name":5,"class":6},1]