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Gram-negative organism not susceptible to any oral antibiotics\n* Gram-negative organism not susceptible to any IV antibiotics\n* Polymicrobial bloodstream infection\n\n  * The following patients with polymicrobial infections remain eligible for enrollment: (1) more than one morphology or species of a gram-negative organism (except for Acinetobacter baumannii or Stenotrophomonas maltophilia), (2) a single positive blood culture with a common commensal organism (grown in addition to an Enterobacterales species or Pseudomonas aeruginosa\n* Allergy or contraindication rendering no oral option or no IV option for therapy with the listed antibiotic agents.\n* Anticipated duration of therapy greater than 14 days\n* Central nervous system infection\n* Absolute neutrophil count of \\\u003C500 cells\u002FmL or anticipated to reduce to \\\u003C500 cells\u002FmL during the antibiotic treatment course.\n* Receiving hospice care","ALL","18 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