GWAS to Identify Predictive Genetic Factors for the Success of Dietary Intervention in the Treatment of IBS Symptoms

ConditionsIrritable Bowel Syndrome (IBS)Genome-wide Association Study Single Nucleotide Polymorphisms Mediterranean Diet FODMAP Diet

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-65

SponsorAttikon Hospital

About this trial

This is a GWAS that aims to identify possible single nucleotide polymorphisms (SNPs) that are associated with the response in a combined dietary pattern low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols and Meditteranean diet (MED-LFD) in a small group of patients with Irritable Bowel Syndrome (IBS).

Eligibility criteria

Qualifiers

Fulfillment of the Rome IV criteria for IBS

Provision of written informed consent.

Commitment of availability throughout the study period.

IBS-SSS > 175

Disqualifiers

Any concomitant disease requiring specialized nutrition (e.g. renal failure, diabetes, celiac disease, cerebrovascular disease of the central nervous system, major surgical cavity).

Pregnancy.

Breastfeeding.

Trial design

Treatments tested in this trial

Med-LFD intervention

Treatment groups

100 Participants

are divided into 1 treatment group

Locations

Attikon General University Hospital of Athens12462, Athens Greece

Sponsors and collaborators

Attikon Hospital

Lead sponsor

Source ClinicalTrials.gov