About this trial

This study aims to construct a structuralized follow-up model for survivors of childhood hematological malignancies in China. Using a multicenter prospective cohort design, it will identify the burden and risk factors of late effects. The study hypothesizes that a standardized follow-up path managed by an electronic platform will improve follow-up compliance and reduce the missed diagnosis rate of late effects.

Eligibility criteria

Qualifiers

Diagnosed with childhood hematological malignancies (ALL, AML, Lymphoma, etc.), Completed primary treatment for ≥12 months.

Age 1-21 years.

Capable of completing follow-up and data collection.

Informed consent signed.

Disqualifiers

Severe organ failure preventing follow-up.

Major genetic or systemic diseases affecting growth/organ function.

Expected poor compliance or refusal to participate.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

400 Participants
are grouped into 2 trial groups

Locations

3
Children's hospital, Zhejiang University School of Medicine310000, HangzhouZhejiang, China
Hangzhou Children's Hospital310014, HangzhouZhejiang, China
Affiliated Women and Children's Hospital of Ningbo University315000, NingboZhejiang, China

Sponsors and collaborators

The Children's Hospital of Zhejiang University School of Medicine

Lead sponsor

Ningbo Women & Children's Hospital

Collaborator

Hangzhou Children's Hospital

Collaborator