[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586093":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":108,"collaborators":18,"id":110,"slug":18,"hasResults":111,"nctId":112,"briefTitle":113,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":111,"sex":116,"minAge":117,"maxAge":18,"enrollmentInfo":118,"targetDuration":18,"studyType":121,"phases":122,"briefSummary":124,"conditions":125,"keywords":129,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":145},{"fullName":5,"class":6},"University Hospital, Limoges","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention arm","EXPERIMENTAL","As soon as an eligible patient is identified by the nurse, in addition to the classic hemodynamic parameters measured in all patients, a measurement of the peripheral perfusion index (from 1 sec to 10 sec) and marbling assessment (scale from 0 to 5) will be performed. This measurement will be validated by the senior doctor of the Sepsis Department. When the peripheral perfusion index will be ≥ 3 sec and\u002For the marbling score ≥ 1, a first vascular filling test of 500 cc over 30 minutes will be started, regardless of the value of the hemodynamic parameters.",[13],"Diagnostic Test: measurement of the peripheral perfusion index and marbling assessment",{"label":15,"type":16,"description":17,"interventionNames":18},"Control arm","NO_INTERVENTION","Patients will benefit from treatment according to current standards of care",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DIAGNOSTIC_TEST","measurement of the peripheral perfusion index and marbling assessment","in addition to the classic hemodynamic parameters measured in all patients, a measurement of the peripheral perfusion index (from 1 sec to 10 sec) and marbling assessment (scale from 0 to 5) will be performed",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Anaelle NARDOT-SUCHAUD","CONTACT","0519761835","Anaelle.NARDOT-SUCHAUD@chu-limoges.fr",[32,48,60,72,84,96],{"facility":33,"status":34,"city":35,"state":18,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Brive Hospital","RECRUITING","Brivé","19100","France",{"type":39,"coordinates":40},"Point",[41,42],-2.00321,47.48857,{"lat":42,"lon":41},[45],{"name":46,"role":47,"phone":18,"phoneExt":18,"email":18},"Pierrick BARDOU","PRINCIPAL_INVESTIGATOR",{"facility":49,"status":34,"city":50,"state":18,"zip":51,"country":37,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"Guéret Hospital","Guéret","23000",{"type":39,"coordinates":53},[54,55],1.87166,46.17185,{"lat":55,"lon":54},[58],{"name":59,"role":47,"phone":18,"phoneExt":18,"email":18},"Amaury GALAUD",{"facility":61,"status":34,"city":62,"state":18,"zip":63,"country":37,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Limoges University Hospital","Limoges","87000",{"type":39,"coordinates":65},[66,67],1.24759,45.83362,{"lat":67,"lon":66},[70],{"name":71,"role":47,"phone":18,"phoneExt":18,"email":18},"Manon DUMOLARD",{"facility":73,"status":34,"city":74,"state":18,"zip":75,"country":37,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Saint Junien Hospital","Saint-Junien","87200",{"type":39,"coordinates":77},[78,79],0.90158,45.88746,{"lat":79,"lon":78},[82],{"name":83,"role":47,"phone":18,"phoneExt":18,"email":18},"Morgan GAURIAT",{"facility":85,"status":34,"city":86,"state":18,"zip":87,"country":37,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Tulle Hospital","Tulle","19012",{"type":39,"coordinates":89},[90,91],1.77233,45.26582,{"lat":91,"lon":90},[94],{"name":95,"role":47,"phone":18,"phoneExt":18,"email":18},"Philippe DUPUY",{"facility":97,"status":34,"city":98,"state":18,"zip":99,"country":37,"cosmosGeoPoint":100,"geoPoint":104,"contacts":105},"Ussel Hospital","Ussel","19200",{"type":39,"coordinates":101},[102,103],2.30917,45.54804,{"lat":103,"lon":102},[106],{"name":107,"role":47,"phone":18,"phoneExt":18,"email":18},"Cyril MOESCH",{"type":109,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100586093",false,"NCT06910891","Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients","HEMOCAP","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Admitted to the Emergency Department for suspected Sepsis for less than 6 hours according to international Sepsis-3 definitions (high probability of infection defined by a fever greater than or equal tol to 38.3°C with a suspected infectious source + Score NEWS 2 greater than or equal to 2)\n3. Affiliated to a social security system\n4. Having agreed to participate in this study\n\nExclusion Criteria:\n\n1. Patient with arterial hypotension (SBP ≤ 100 mmHg) on admission\n2. Patient having already received a 500mL filling test over 30 minutes\n3. Patients moribund according to the investigator\n4. Pregnancy or breastfeeding\n5. Patient under guardianship, curatorship or safeguard of justice","ALL","18 Years",{"count":119,"type":120},556,"ESTIMATED","INTERVENTIONAL",[123],"NA","Despite early treatment, the deterioration and mortality of sepsis patients remains high. A possible explanation could be persistent tissue hypoperfusion, or undetected in the early phase despite the normalization of macro-hemodynamic parameters. This interventional study evaluates the impact of measuring microcirculation parameters by nurses on patient prognosis through early initiation of vascular filling.",[126,127,128],"Sepsis","Emergency Care","Microcirculation",[130,131,132,133,134,135],"microcirculation","septic patient","organ dysfunction","sepsis","peripheral perfusion index","emergency unit","2025-11-18",{"date":138,"type":139},"2025-11-21","ACTUAL",{"date":141,"type":139},"2025-09-20",{"date":143,"type":120},"2027-03-28",{"name":5,"class":6},6]