[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616588":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":81,"collaborators":25,"id":85,"slug":25,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":25,"eligibilityCriteria":90,"healthyVolunteers":86,"sex":91,"minAge":92,"maxAge":25,"enrollmentInfo":93,"targetDuration":25,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":105,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"High-flow nasal cannula Group","EXPERIMENTAL","In this group, patients use the High-flow nasal cannula",[13],"Device: High-flow nasal cannula Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Regular Nasal Cannula Group","ACTIVE_COMPARATOR","In this group, patients use the regular nasal cannula for oxygenation.",[19],"Device: Regular Nasal Cannula",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Using High-flow nasal cannula oxygenation",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Regular Nasal Cannula","Using regular nasal cannula for oxygenation",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Diansan Su, Chief Physician","CONTACT","+8618616514088","diansansu@yahoo.com",[37,53,67],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"The First Affiliated Hospital, Zhejiang University School of Medicine","RECRUITING","Hangzhou","Zhejiang","310000","China",{"type":45,"coordinates":46},"Point",[47,48],120.16142,30.29365,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":34,"phoneExt":25,"email":35},"Diansan Su, Dr",{"facility":54,"status":39,"city":55,"state":41,"zip":56,"country":43,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"The First Hospital Of Jiaxing","Jiaxing","314000",{"type":45,"coordinates":58},[59,60],120.75,30.7522,{"lat":60,"lon":59},[63],{"name":64,"role":33,"phone":65,"phoneExt":25,"email":66},"Huadong Ni, Dr","+86 15068386387","huadongni@zjxu.edu.cn",{"facility":68,"status":39,"city":69,"state":41,"zip":70,"country":43,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Quzhou People's Hospital","Quzhou","324000",{"type":45,"coordinates":72},[73,74],118.86861,28.95944,{"lat":74,"lon":73},[77],{"name":78,"role":33,"phone":79,"phoneExt":25,"email":80},"Huiling Yu, Dr","+86 13059727022","1608980221@qq.com",{"type":82,"investigatorFullName":83,"investigatorTitle":84,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Diansan Su","Chief Physician,Researcher","100616588",false,"NCT07307560","High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients","High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients: A Multicenter Randomized Trial","Inclusion Criteria:\n\n* Age ≥18 years.\n* STOP-Bang score ≥5.\n* Scheduled for sedated gastrointestinal endoscopy (gastroscopy, colonoscopy, or combined gastroscopy + colonoscopy).\n* The estimated duration of the procedure does not exceed 45 minutes.\n* Patients have signed the informed consent form.\n\nExclusion Criteria:\n\n* Coagulation disorders or bleeding tendency (e.g., oral\u002Fnasal bleeding risk, mucosal injury, space-occupying obstructions).\n* Active upper respiratory tract infection (oral, nasal, or pharyngeal), or fever (core temperature \\>37.5°C).\n* Chronic obstructive pulmonary disease or other acute\u002Fchronic pulmonary diseases requiring long-term or intermittent oxygen therapy, or preoperative SpO₂ ≤ 92% on room air.\n* Severe organ dysfunction, including: Cardiac insufficiency (\\\u003C4 METs), Severe renal insufficiency (requiring dialysis), Diagnosed severe hepatic insufficiency, Increased intracranial pressure, ASA physical status ≥ IV.\n* Confirmed pregnancy or current breastfeeding.\n* Known allergy to sedatives (e.g., propofol) or medical adhesives.\n* Multiple traumatic injuries.\n* Current participation in another clinical trial.\n* Other conditions deemed unsuitable by the investigator","ALL","18 Years",{"count":94,"type":95},600,"ESTIMATED","INTERVENTIONAL",[98],"NA","Hypoxia represents the most frequent adverse event during propofol-sedated gastrointestinal endoscopy. The STOP-BANG questionnaire serves as a widely adopted, straightforward tool for screening obstructive sleep apnea (OSA) risk, with a score ≥5 identifying high-risk OSA patients who are particularly susceptible to hypoxia under sedation. Although preliminary research from our team suggests that High-Flow Nasal Cannula (HFNC) may lower the incidence of hypoxemia, evidence remains limited and inconsistent in studies specifically targeting high-risk OSA populations. Therefore, this multicenter randomized controlled trial aims to evaluate whether HFNC can effectively reduce the occurrence of hypoxia during sedated gastrointestinal endoscopy in patients identified as high-risk for OSA.",[101,102,103,104],"Hypoxia","Esophageal Cancer","Gastric Cancer (Diagnosis)","Obstructive Sleep Apnea (OSA)",[106,101,104,107],"Sedation","Gastrointestinal Endoscopy","2026-05-01",{"date":110,"type":111},"2026-05-04","ACTUAL",{"date":113,"type":111},"2025-12-21",{"date":115,"type":95},"2026-12-01",{"name":5,"class":6},3]