About this trial
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye.
The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea.
The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease.
The purpose of this project is to observe structures that are not detectable with routinely used systems.
Eligibility criteria
Qualifiers
People over 18
Patient with a pathology affecting the eye or healthy volunteer
Participant who signed the consent
Beneficiaries of the health insurance
Disqualifiers
Patients with a history of photosensitivity.
Patients who have just received a photodynamic therapy treatment (
Patients taking drugs with photosensitivity as a side effect.
Persons with pacemakers or other implanted electronic medical device
Trial design
Treatments tested in this trial
- High-resolution retinal imaging through adaptive optics
- High-resolution retinal imaging through holographic systems
Treatment groups
Locations
1Sponsors and collaborators
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Lead sponsor