[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100537274":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":37,"locations":47,"responsibleParty":62,"collaborators":64,"id":70,"slug":26,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":26,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":50,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"East and North Hertfordshire NHS Trust","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment","EXPERIMENTAL","Manuka honey, 15ml, three times a day, for 14 days. To be kept on the tongue for at least 10 seconds prior to swallowing.",[13],"Dietary Supplement: Manuka honey MGO 1000",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring, 15ml, three times a day, for 14 days.\n\nTo be kept on the tongue for at least 10 seconds prior to swallowing.",[19],"Dietary Supplement: Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Manuka honey MGO 1000","Natural Manuka honey, produced in New Zealand. With MGO content ≥ 1000.",[9],null,{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Sugar-based syrup, thickened with sodium alginate and flavoured with honey flavouring",[15],[31,34],{"name":32,"affiliation":5,"role":33},"Phillip Smith, PhD","STUDY_DIRECTOR",{"name":35,"affiliation":5,"role":36},"George Mochloulis, MD","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},"Carina Cruz","CONTACT","07917534555","carina.cruz@nhs.net",{"name":44,"role":40,"phone":45,"phoneExt":26,"email":46},"Toral Odedra","07918 360 060","toral.odedra@nhs.net",[48],{"facility":49,"status":50,"city":51,"state":26,"zip":52,"country":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Lister Hospital","RECRUITING","Stevenage","SG1 4AB","United Kingdom",{"type":55,"coordinates":56},"Point",[57,58],-0.20256,51.90224,{"lat":58,"lon":57},[61],{"name":44,"role":40,"phone":45,"phoneExt":26,"email":46},{"type":63,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[65,68],{"name":66,"class":67},"Manuka Doctor UK Ltd","UNKNOWN",{"name":69,"class":6},"National Institute for Health Research, United Kingdom","100537274",false,"NCT06275698","HONEY for the Treatment of POst-Tonsillectomy Pain","HONEY for the Treatment of POst-Tonsillectomy Pain - a Double-blind, Randomised, Placebo Controlled, Single Site Trial","HONEY-POT","Inclusion Criteria:\n\n* Adult (≥18years old at the time of giving consent)\n* Consented and listed for bilateral tonsillectomy or adenotonsillectomy\n* Tonsillectomy performed within the trial study period\n\nExclusion Criteria:\n\n* Any concurrent Head \\& Neck (H\\&N) malignancy\n* Unilateral tonsillectomy\n* Pregnancy\n* Concurrent pharyngeal or upper aerodigestive tract biopsy\n* Robotic tonsillectomy\n* Previous H\\&N malignancy\n* Previous H\\&N radiotherapy\n* Type 1\u002F2 diabetes mellitus\n* Known allergy to bee related products\n* Known allergy to golden syrup\n* History of chronic pain\n* History of fibromyalgia\n* Current usage of chronic (\\>6weeks) analgesia\n* High-risk anaesthetic patients\n* Children or adolescents \\\u003C18years old\n* Adults unable to consent for themselves",true,"ALL","18 Years",{"count":81,"type":82},100,"ESTIMATED","INTERVENTIONAL",[85],"NA","Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative outcomes.\n\nMain aim is to investigate a potential improvement in post-tonsillectomy pain control, with a low cost and freely available alternative to conventional analgesics. Recent systematic review and multidisciplinary consensus suggest a potential role for the inclusion of honey for this purpose. Clinical efficacy over placebo remains to be conclusively demonstrated in robust clinical trials.",[88,89],"Post Surgical Pain","Analgesia",[91,92,93,94],"Post-tonsillectomy pain","Tonsil surgery","Manuka honey","Honey","2025-04-28",{"date":97,"type":98},"2025-04-29","ACTUAL",{"date":100,"type":98},"2023-09-04",{"date":102,"type":82},"2025-09-04",{"name":5,"class":6},1]