[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573347":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":28,"centralContacts":28,"locations":34,"responsibleParty":52,"collaborators":28,"id":56,"slug":28,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":28,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":28,"overallStatus":36,"whyStopped":28,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Vienna","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Xanthohumol","EXPERIMENTAL","Participants receive a study drink supplemented with Xanthohumol (0 mg = Placebo or 0.75 mg soluble Xanthohumol)",[13],"Dietary Supplement: Xanthohumol",{"label":15,"type":10,"description":16,"interventionNames":17},"Iso-alpha Acids","Participants receive a study drink supplemented with Iso-alpha Acids (0 mg = Placebo or 45 mg Iso-alpha Acids)",[18],"Dietary Supplement: Iso-alpha Acids",{"label":20,"type":10,"description":21,"interventionNames":22},"Xanthohumol + Iso-alpha Acids","Participants receive a study drink supplemented with Xanthohumol + Iso-alpha Acids (0 mg = Placebo or 0.75 mg + 45 mg soluble Xanthohumol + Iso-alpha Acids)",[23],"Dietary Supplement: Xanthohumol + Iso-alpha Acids",[25,29,31],{"type":26,"name":9,"description":11,"armGroupLabels":27,"otherNames":28},"DIETARY_SUPPLEMENT",[9],null,{"type":26,"name":15,"description":16,"armGroupLabels":30,"otherNames":28},[15],{"type":26,"name":20,"description":32,"armGroupLabels":33,"otherNames":28},"Participants receive a study drink supplemented with Xanthohumol and Iso-alpha Acids (0 mg = Placebo or 0.75 mg + 45 mg soluble Xanthohumol + Iso-alpha Acids)",[20],[35],{"facility":5,"status":36,"city":37,"state":28,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Vienna","1090","Austria",{"type":41,"coordinates":42},"Point",[43,44],16.37208,48.20849,{"lat":44,"lon":43},[47],{"name":48,"role":49,"phone":50,"phoneExt":28,"email":51},"Ina Bergheim, Prof. Dr.","CONTACT","+43-1-4277-54981","ina.bergheim@univie.ac.at",{"type":53,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":28,"oldOrganization":28},"PRINCIPAL_INVESTIGATOR","Prof. Dr. Ina Bergheim","Principal Investigator","100573347",false,"NCT06745102","Hop Compounds on the Immune System in Overweight People","Effect of Iso-alpha Acids and Xanthohumol on the Human Immune System in Overweight People With the Onset of Metabolic Diseases","ÜG","Inclusion Criteria:\n\n* BMI 25 - 29,9 kg\u002Fm²\n\nas well as one or more of the following incipient metabolic diseases:\n\n* pre-diabetes (fasting blood glucose 100-125 mg\u002FdL),\n* fatty liver (grade 1-3),\n* high-normal blood pressure to mild hypertension (grade 1, systolic 140-159 mmHg)\n\nExclusion Criteria:\n\n* History of diseases that could falsify the study results\n* inflammatory bowel diseases\n* malignant diseases of the gastrointestinal tract\n* food allergies\n* malabsorption\n* kidney or liver disease (except simple fatty liver)\n* symptomatic heart failure\n* Taking medication to treat these diseases\n* Consumption of special diets (e.g. vegan, gluten-free)\n* Pregnancy","ALL","18 Years","75 Years",{"count":67,"type":68},24,"ESTIMATED","INTERVENTIONAL",[71],"NA","The aim of the present study is to determine the effect of Iso-alpha Acids and Xanthohumol from hops on the immune response in overweight participants.",[74],"Inflammatory Response","2025-04-10",{"date":77,"type":78},"2025-04-15","ACTUAL",{"date":80,"type":78},"2024-02-01",{"date":82,"type":68},"2025-12-30",{"name":5,"class":6},1]