[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100610290":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":17,"centralContacts":23,"locations":33,"responsibleParty":78,"collaborators":82,"id":86,"slug":17,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":87,"sex":93,"minAge":94,"maxAge":95,"enrollmentInfo":96,"targetDuration":17,"studyType":99,"phases":100,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":36,"whyStopped":17,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Shady Grove Fertility Reproductive Science Center","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Holiday","Patients will undergo a 2 month drug holiday (pause) with combined hormonal contraceptives prior to planned oocyte cryopreservation",[12],"Other: OCP pause",{"label":14,"type":15,"description":16,"interventionNames":17},"Immediate Start","NO_INTERVENTION","Patients will immediately begin planned oocyte cryopreservation after discontinuation of prolonged combined hormonal contraceptive",null,[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":17},"OCP pause","Subjects in the study arm will be asked to discontinue combined hormonal contraceptives (CHC) for 2 months prior to planned oocyte cryopreservation",[9],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":17,"email":28},"Tasha Newsome, Clinical Research Supervisor","CONTACT","301-545-1289","Tasha.Newsome@sgfertility.com",{"name":30,"role":26,"phone":31,"phoneExt":17,"email":32},"Seth J Barishansky, MD","475-267-9469","HolidayStudy@USFertility.com",[34,49,64],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Yale Fertility Center","RECRUITING","Orange","Connecticut","06477","United States",{"type":42,"coordinates":43},"Point",[44,45],-73.02566,41.27843,{"lat":45,"lon":44},[48],{"name":30,"role":26,"phone":31,"phoneExt":17,"email":32},{"facility":50,"status":36,"city":51,"state":52,"zip":53,"country":40,"cosmosGeoPoint":54,"geoPoint":58,"contacts":59},"Shady Grove Fertility Rockville","Rockville","Maryland","20850",{"type":42,"coordinates":55},[56,57],-77.15276,39.084,{"lat":57,"lon":56},[60,62],{"name":61,"role":26,"phone":27,"phoneExt":17,"email":28},"Tasha Newsome, 301-545-1289",{"name":63,"role":26,"phone":17,"phoneExt":17,"email":32},"Amalia Namath, MD",{"facility":65,"status":66,"city":67,"state":67,"zip":68,"country":40,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Reproductive Medicine Associates of New York","NOT_YET_RECRUITING","New York","10022",{"type":42,"coordinates":70},[71,72],-74.00597,40.71427,{"lat":72,"lon":71},[75],{"name":76,"role":26,"phone":77,"phoneExt":17,"email":32},"Miriam Andrusier, MD","212-756-5777 ext 88270",{"type":79,"investigatorFullName":80,"investigatorTitle":81,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"PRINCIPAL_INVESTIGATOR","Kate Devine","Medical Director and Chief Research Officer, USFertility",[83],{"name":84,"class":85},"EMD Serono","INDUSTRY","100610290",false,"NCT07225660","Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)","A Randomized Blinded Controlled Trial Assessing Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)","HOLIDAY","Inclusion Criteria:\n\n1. Ovary-bearing individuals 18 to 40 years of age.\n2. BMI \\\u003C 40 kg\u002Fm2\n3. Non-smoker for at least 3 months prior to study enrollment.\n\nExclusion Criteria:\n\n1. BMI greater than or equal to 40 kg\u002Fm2\n2. Current Smoker\n3. Any contraindications to ovarian stimulation or outpatient egg retrieval under anesthesia","FEMALE","18 Years","40 Years",{"count":97,"type":98},394,"ESTIMATED","INTERVENTIONAL",[101],"NA","HOLIDAY is a two-arm, parallel-group, multi-center, randomized trial in which subjects undergoing planned oocyte cryopreservation will be randomized to receive either a 2-month pause of Combined Hormonal Contraceptives (CHC) or immediate start (without a pause).",[104],"Fertility Preservation",[106],"planned oocyte cryopreservation","2026-02-26",{"date":109,"type":110},"2026-03-02","ACTUAL",{"date":112,"type":110},"2026-02-25",{"date":114,"type":98},"2027-07-01",{"name":5,"class":6},3]