[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590845":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":75,"collaborators":26,"id":77,"slug":26,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":78,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":26,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":26,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Duke University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of Care","PLACEBO_COMPARATOR","The control arm will receive standard counseling regarding post operative HRT by their gynecologic oncologist during their visit, as well as standardized written education in their after-visit summary.",[13],"Behavioral: SOC Arm",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental","EXPERIMENTAL","The experimental arm will receive standard verbal counseling and written education plus the video-based educational aid describing the risks and benefits of HRT.",[19],"Behavioral: Experimental Arm",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Experimental Arm","Participants will be randomized to SOC plus the video.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"SOC Arm","Participants will be randomized to SOC counseling.",[9],[32],{"name":33,"affiliation":5,"role":34},"Laura Havrilesky","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Amelia Scott","CONTACT","(919) 613-4584","amelia.lorenzo@duke.edu",[42,61],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"UNC Chapel Hill Health System","RECRUITING","Chapel Hill","North Carolina","27514","United States",{"type":50,"coordinates":51},"Point",[52,53],-79.05584,35.9132,{"lat":53,"lon":52},[56,60],{"name":57,"role":38,"phone":58,"phoneExt":26,"email":59},"Katherine Tucker, MD","919-966-2131","Katherine.Tucker2@unchealth.unc.edu",{"name":57,"role":34,"phone":26,"phoneExt":26,"email":26},{"facility":62,"status":44,"city":63,"state":46,"zip":64,"country":48,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Duke University Health System","Durham","27710",{"type":50,"coordinates":66},[67,68],-78.89862,35.99403,{"lat":68,"lon":67},[71,73],{"name":37,"role":38,"phone":72,"phoneExt":26,"email":40},"919-613-4584",{"name":74,"role":34,"phone":26,"phoneExt":26,"email":26},"Laura Havrilesky, MD",{"type":76,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100590845",false,"NCT06972719","Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy","Patient Centered Education About Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy: a Pilot Randomized Controlled Trial","BRCA HRT Pilot","Inclusion Criteria:\n\n* BRCA1 or BRCA2 germline mutation\n* scheduled for a risk-reducing salpingo-oophorectomy (RRSO) by Duke Gynecologic Oncologist\n* premenopausal\n\nExclusion Criteria:\n\n* personal history of cancer\n* postmenopausal\n* \\>50 years old\n* unable to provide informed consent in English","FEMALE","19 Years","50 Years",{"count":88,"type":89},50,"ESTIMATED","INTERVENTIONAL",[92],"NA","The goal of this study is to develop an educational aid about hormone replacement therapy that physicians can share with patients as part of their pre-surgical counseling for a risk-reducing salpingo-oophorectomy (RRSO).",[95,96],"BRCA1 Mutation","BRCA2 Mutation","2026-03-25",{"date":99,"type":100},"2026-03-27","ACTUAL",{"date":102,"type":100},"2025-09-30",{"date":104,"type":89},"2026-12-31",{"name":5,"class":6},2]