[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575199":3},{"organization":4,"outcomesModule":7,"designInfo":24,"detailedDescription":23,"studyPopulation":23,"armGroups":31,"interventions":42,"overallOfficials":23,"centralContacts":49,"locations":23,"responsibleParty":56,"collaborators":23,"id":58,"slug":23,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":23,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":23,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":83,"whyStopped":23,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":23},{"fullName":5,"class":6},"Yeditepe University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":19,"otherOutcomes":23},[9,13,16],{"measure":10,"description":11,"timeFrame":12},"Muscle Strength Assessment","Muscle strength is an important component of health. Muscle weakness is seen in the presence of neurologicaldiseases and therefore muscle strength measurement is important for general health assessment. The most common equipment or methods that provide quantitative measurements of strength, such as isokinetic and portable dynamometers, have been shown to provide valid and reliable measurements. The muscle strengths of the participants in the lower extremity (hip flexor, extensor, abductor and adductor, knee flexor and extensor, ankle dorsi-plantar flexor) muscle groups will be measured with a handheld dynamometer.","up to 8 weeks",{"measure":14,"description":15,"timeFrame":12},"Timed Up and Go Test (TUG)","TUG is a rapid test used in clinic as an outcome measure to assess functional mobility as well as static and dynamic balance. It's based on the length of time which takes for an individual to get up from a chair, walk 3 meters at a comfortable (or fastest) pace, turn (or touch the wall), walk to chair and sit down again.",{"measure":17,"description":18,"timeFrame":12},"Berg Balance Scale (BBS)","The BBS, developed by Berg et al (1995) and used in the assessment of balance, is a four-point scale that rates patients' balance from easy to difficult (0: cannot do, 4: does independently). During the test consisting of 14 items, steps, rulers, stopwatches and chairs are used. The test evaluates postural control and fall risk. The maximum total score is 56 points. 0-20: high fall risk, 21-40: moderate fall risk, 41-56: low fall risk. The Turkish validity and reliability of the scale was made by Şahin et al (2008).",[20],{"measure":21,"description":22,"timeFrame":12},"fMRI scan","High-resolution (1 x 1 x 1 mm isotropic) sagittal 190 slices will be acquired with a T1-weighted imaging sequence (TR\u002FTE: 7.7\u002F3.7 ms;, FA: 8°; FOV: 256 x 256). Functional resting state data will be acquired with a single-shot echo planar imaging (EPI) sequence of 300 dynamic acquisitions consisting of 35 slices of 4 mm thickness (TR\u002FTE: 2230\u002F30 ms, FA: 77°; matrix: 80x80) and will last approximately 11 minutes. Magnetic field maps will be recorded in order to correct signal distortions caused by tissue inhomogeneities in the magnetic field during the analysis phase before functional acquisition. Participants will be asked to fix their gaze on a point by keeping their eyes open during functional acquisitions. Participants will be informed that they can close their eyes and rest during the other stages of the acquisitions. fMRI acquisitions will be completed in approximately 30 minutes, including the preparation stages. The MRI acquisition sequences will be as follows: Survey, Resting S",null,{"allocation":25,"interventionModel":26,"interventionModelDescription":23,"primaryPurpose":6,"observationalModel":23,"timePerspective":23,"maskingInfo":27},"RANDOMIZED","PARALLEL",{"masking":28,"maskingDescription":23,"whoMasked":29},"SINGLE",[30],"PARTICIPANT",[32,38],{"label":33,"type":34,"description":35,"interventionNames":36},"Serious Game Group","EXPERIMENTAL","BecureBalance and WesenseSystems will be used.Games'll be chosen to improve balance and empowerment,and game levels will be adjusted according to the condition of the participants.Balance Adventure is a game that involves transferring weight in 4 directions.At level 1,the goal is to reach the exit by collecting all the stars. At level 3,the goal is to collect stars on a moving surface and move the ball without dropping it.Balance Surf game is played with weight transfer from right to left and forward.The aim of the game is to earn points by steering the surfboard on the screen,collecting stars and gift wrap objects.Sizing Ball and Aerobat games are played by connecting a wearable sensor to the muscle group that the participants want to exercise.By calibrating this sensor, we can assume the angle we want is 0,and when more than the angle we set is made,movement will be revealed in the game.For this,lower extremity muscles will be exercised with these games by wearing a resistance band.",[37],"Other: Virtual Reality based",{"label":39,"type":6,"description":40,"interventionNames":41},"Control Group","Participants in the control group will receive a total of 16 sessions of structured NGT-based exercise applications prepared by the researchers.For this, involving balance and strengthening'll be applied, focusing mainly on lower extremity movements. For warm-up exercises, trunk rotation, shoulder rotation, hip rotation and toe-to-toe elevation and descent'll be performed for 10 minutes.Strengthening exercises'll mostly focus on the lower extremity muscles.These exercises'll be practiced for 20 minutes, and the participants'll be given the following exercises while the weight is tied. Each exercise'll be done in 2 sets of 10 repetitions.Balance exercises'll be practiced statically and dynamically for 20 minutes with 2 sets of 10 repetitions.",[37],[43],{"type":6,"name":44,"description":45,"armGroupLabels":46,"otherNames":47},"Virtual Reality based","Participants will receive treatment by a specialist physiotherapist for a total of 16 sessions, 2 days a week on non-consecutive days for 8 weeks. Both groups will receive neurodevelopmental treatment (NGT) for 16 sessions. While the control group will receive traditional balance training in each session, the VR group will play virtual reality-based games.",[39,33],[48],"Neurodevelopmental based",[50],{"name":51,"role":52,"phone":53,"phoneExt":54,"email":55},"Simay Atıcı, PhD C","CONTACT","+902165780000","3037","simayaticii@hotmail.com",{"type":57,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100575199",false,"NCT06769178","How Much Virtual Reality Intervention Improve the Balance of Patients with Cerebral Palsy","Effect of Virtual Reality-Based Interventions on Clinical and Neuroplasticity, Brain Functional Resting State Networks in Cerebral Palsy Rehabilitation","Inclusion Criteria:\n\nBeing diagnosed with unilateral spastic type cerebral palsy (hemiplegic type) \u002F Being between the ages of 18-30 \u002F Being able to walk independently (GMFCS I-II) \u002F Not having Botox application in the last six months \u002F Not using any medication that will affect the study process\n\nExclusion Criteria:\n\nHaving a history of epileptic attacks \u002F Having \\>2 spasticity in any joint according to the modified Ashworth scale \u002F Having severe depression according to the Beck Depression Inventory \u002FHaving hearing-vision problems","ALL","18 Years","30 Years",{"count":68,"type":69},24,"ESTIMATED","INTERVENTIONAL",[72],"NA","The purpose of this clinical study is to investigate how effective virtual reality applications are in adult cerebral palsy rehabilitation.\n\nThe main questions it aims to answer are:\n\nDo virtual reality interventions (of Becure Balance and Becure Wesense Systems) improve balance and is this improvement reflected in the clinic? Is there a change in brain functional resting state networks after virtual reality interventions?",[75],"Cerebral Palsy",[77,78,79,80,81,82],"adult cerebral palsy","functional magnetic reasonance imaging","virtual reality","becure systems","balance","resting state functional magnetic reasonance imaging","NOT_YET_RECRUITING","2025-01-08",{"date":86,"type":87},"2025-01-10","ACTUAL",{"date":89,"type":69},"2025-06",{"date":91,"type":69},"2026-12",{"name":5,"class":6}]