[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586196":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":25,"locations":32,"responsibleParty":48,"collaborators":50,"id":58,"slug":11,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":11,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":11,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":11,"overallStatus":35,"whyStopped":11,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Ottawa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Normoxia","EXPERIMENTAL",null,[13],"Other: Normoxia",{"label":15,"type":10,"description":11,"interventionNames":16},"Hypoxia (simulated altitude of 5000 meters above sea-level)",[17],"Other: Hypoxia (simulated altitude of 5000 meters above sea-level)",[19,22],{"type":6,"name":9,"description":20,"armGroupLabels":21,"otherNames":11},"Participants will undergo a 6-hour passive exposure to normoxia in a climate-controlled environmental chamber maintained at 22°C with 30% relative humidity. They will remain in a fasted state throughout the exposure period.",[9],{"type":6,"name":15,"description":23,"armGroupLabels":24,"otherNames":11},"Participants will undergo a 6-hour passive exposure to a simulated altitude of 5000 meters above sea-level in a climate-controlled environmental chamber maintained at 22°C with 30% relative humidity. They will remain in a fasted state throughout the exposure period.",[15],[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Pascal Imbeault, PhD","CONTACT","6135625800","7290","imbeault@uottawa.ca",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Behavioural and Metabolic Research Unit, School of Human Kinetics, Faculty of Health Sciences, University of Ottawa","RECRUITING","Ottawa","Ontario","K1N 6N5","Canada",{"type":41,"coordinates":42},"Point",[43,44],-75.69812,45.41117,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},{"type":49,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[51,53,55],{"name":52,"class":6},"Natural Sciences and Engineering Research Council, Canada",{"name":54,"class":6},"Hopital Montfort",{"name":56,"class":57},"Institut du Savoir Montfort","UNKNOWN","100586196",false,"NCT06912230","Hypoxia, Appetite, and Energy Intake in Young Female Adults","Appetite and Energy Intake in Young Female Adults During and After Simulated High-Altitude","Inclusion Criteria:\n\n* English or French speaking\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* History or evidence of chronic disease\n* Current use of hypolipemic medication\n* Current use of hormonal contraceptives\n* Current use of antidepressants\n* Current use of anticoagulants\n* Ongoing smoking status\n* Experiencing pregnancy, puerperium, or irregular menstrual cycles",true,"FEMALE","18 Years","30 Years",{"count":69,"type":70},10,"ESTIMATED","INTERVENTIONAL",[73],"NA","The goal of this clinical trial is to investigate the effects of acute passive continuous hypoxemia (simulated high-altitude at rest) on appetite and energy intake in healthy young female adults. The main questions it aims to answer are:\n\n* Does six hours of simulated high-altitude (5000 meters) reduce scores of subjective appetite and energy intake?\n* Do changes in appetite and energy intake persist in the hours following the end of hypoxic exposure? Researchers will compare the effects of simulated high-altitude to a control normoxia (sea-level) condition to see if exposure to low oxygen levels independently affect appetite and energy intake.\n\nParticipants will:\n\n* Visit the laboratory for a preliminary screening session to assess eligibility.\n* Undergo two randomized, single-blind, experimental sessions consisting of six hours of passive exposure to normoxia or hypoxia in a climate-controlled chamber.\n* Consume foods provided from a curated list, served in ad libitum quantities, after leaving the laboratory to assess post-exposure energy intake.",[76,77,78,79],"Hypoxia","Altitude","Appetite","Energy Intake","2025-03-28",{"date":82,"type":83},"2025-04-04","ACTUAL",{"date":85,"type":83},"2024-11-13",{"date":87,"type":70},"2025-12",{"name":5,"class":6},1]