Identification of Molecular Signatures of High-risk Oncogenic HPV and Study of Their Associations With the Presence of High-grade Lesions and/or Anal Cancer 10 Years After Inclusion in the ANRS IPERGAY Trial

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorANRS, Emerging Infectious Diseases

About this trial

HPVsign is a cross-sectional, non-comparative, multicenter study involving all participants included in the HPV substudy of the ANRS IPERGAY trial. The study proposes to evaluate the cumulative incidence of high-grade lesions and/or anal cancers using high-resolution anoscopy (HRA) during the HPVsign study and/or diagnosed since the end of participation in the ANRS IPERGAY trial.

Eligibility criteria

Qualifiers

Participant in the ANRS IPERGAY clinical trial who was included in the initial HPV sub-study;

Informed and written signed consent

Participant with regular health insurance

Disqualifiers

Participant under guardianship or curatorship

Participant with free State medical assistance

Participant who disagrees with the use of data collected as part of their participation in the ANRS IPERGAY trial.

Trial design

Treatments tested in this trial

  • High-resolution anoscopy

Treatment groups

100 Participants
are divided into 1 treatment group

Locations

3
Hôpital de la Croix Rousse - SMIT69004, Lyon France
Hôpital Saint-Louis - SMIT75010, Paris France
Hôpital Tenon - SMIT75020, Paris France

Sponsors and collaborators

ANRS, Emerging Infectious Diseases

Lead sponsor

INSERM SC10-US19

Collaborator